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INNOVATIVE TECHNIQUES ARE PROPOSED FOR INVESTIGATION IN A PHASE I EFFORT TO DETERMINE PASSIVE RF SURVEILLANCE AND TARGETING SENSORS AND ASSOCAITED METHODOLOGY FOR PERFORMING RAPID AND ACCURAGE MEASUREMENTS OF RANGE/LOCATION OF THREAT RF EMITTERS. THE ESSENTIAL PHYSICAL CONSTRAINTS TO BE OBSERVED ARE SENSOR COMPATIBILITY WITH, AND PORTABILITY OF THE ASSOCIATED RANGE DETERMINATION/PROCESSING EQUIPME ...

A NOVEL BIOELECTRODE WILL BE FABRICATED FROM CONDUCTING POLYMERS. UNDER PROPER CONDITIONS, THIS BIOELECTRODE CAN BEELECTROCHEMICALLY REDUCED WITH RESULTING INCORPORATION OF NEUROTRANSMITTERS, SUCH AS ACETYLCHOLINE, -AMINOBUTYRATE, DOPAMINE, OR GLUTAMATE, INTO THE POLYMER MATRIX OF THE BIOELECTRODE. THE NEUROTRANSMITTER CAN REMAIN ENTRAPPED WITHIN THE CONDUCTING POLYMER MATRIX WHEN THE BIOELECTRODE ...

OVER THE PAST FIFTEEN YEARS NUMEROUS IMPLANTABLE BIOSENSORS HAVE BEEN DEVELOPED, BUT THEIR COMMERCIAL VIABILITY IS LIMITED MOSTLY BECAUSE OF FAILURE DUE TO TISSUE OR BODY FLUID CORROSION OVER EXTENDED PERIODS. THE CHALLENGE REMAINS TO DEVELOP A COATING MATERIAL WHICH WILL ADHERE TO THE BIOSENSOR, NOT DEGRADE IN THE PRESENCE OF AN ELECTRIC FIELD, BE THIN ENOUGH TO ALLOW FOR USE WITH MICROELECTRONIC ...

THERE IS A NEED FOR IMPROVING THE FORECASTING OF LOCAL WEATHER ELEMENTS SUCH AS PRECIPITATION, SURFACE TEMPERATURE,ETC. CURRENT FORECASTS ARE MADE BY A STATISTICAL ADAPTATIONOF LARGE SCALE NUMERICAL FORECASTS. WE PROPOSE TO USE, INSTEAD, A MODEL THAT COMPUTES THE PHYSICAL PROCESSES THAT LOCALLY MODULATE THE LARGE SCALE METEOROLOGICAL FIELDS. THEPARAMETERS OF SUCH A MODEL NEED TO BE ADJUSTED TO THE ...

ONE OF THE MOST IMPORTANT CONTRIBUTIONS TO THE RADIATION EXPOSURE OF PERSONNEL ENGAGED IN SPACE FLIGHT IS THE SIGNIFICANT FLUX OF HIGH ENERGY NEUTRONS ARISING FROM BOTH PRIMARY AND SECONDARY SOURCES OF IONIZING RADIATION. PRESENTLY, THERE DOES NOT EXIST A SUITABLE AND COMPACT NEUTRON SENSOR CAPABLE OF BEING INCORPORATED IN A FLIGHT INSTRUMENT TO PROVIDE HIGH QUALITY, REAL TIME MEASUREMENT OF THIS ...

THE DISCOVERY OF SUPERCONDUCTIVITY AT HIGH TEMPERATURES (90 K) IN COPPER CONTAINING CERAMICS HAS RESULTED IN THE RAPID ACCELERATION OF SUPERCONDUCTOR RESEARCH. MUCH OF THISRESEARCH IS BEING DIRECTED AT PRODUCING AND EXAMINING NEW COMPOUNDS BOTH TO IMPROVE PERFORMANCE CHARACTERISTICS AND TOBETTER UNDERSTAND THE PHENOMENON. REALIZING THE POTENTIAL COMMERCIAL BENEFITS OF THIS NEW DISCOVERY DEPENDS AS ...

SCINTILLATION SPECTROMETERS ARE CURRENTLY THE MOST WIDELY USED DEVICES FOR THE DETECTION AND SPECTROMETRY OF ENERGETIC PHOTONS (X-RAYS AND GAMMA RAYS) AT ROOM TEMPERATURE. THEY ARE VERY WIDELY USED IN NUCLEAR AND HIGH ENERGY PHYSICS RESEARCH, MEDICAL IMAGING AND INDUSTRIAL GAUGING APPLICATIONS. RECENTLY, SILICON SEMICONDUCTOR OPTICAL DETECTORS HAVE BEEN USED TO DETECT THE LIGHT PRODUCED BY THE SCI ...

THE SURGICAL REMOVAL OF TUMORS IS ONE OF THE MOST IMPORTANT MEDICAL PROCEDURES IN THE TREATMENT OF CANCER. RECENTLY, RADIOPHARMACEUTICALS HAVE BEEN DEVELOPED THAT ACHIEVE IMPROVED SPECIFICITY AND EFFICIENCY FOR LABELING MALIGNANT TISSUE. THESE IMPROVEMENTS HAVE GENERATED A RESURGENCE OF INTEREST IN THE USE OF HAND-HELD, INTRAOPERATIVE NUCLEAR PROBES TO PROVIDE IN SITU INFORMATION FOR THE DELINEATI ...

THIS PROJECT WILL DEVELOP A WORKING IN VITRO BLOOD-BRAIN BARRIER MODEL WITH ENDOTHELIAL CELLS ISOLATED FROM HUMAN BRAIN MICROVASCULATURE. THIS MODEL WILL ALLOW RAPID ASSESSMENT OF THE EFFICACY OF DRUG DELIVERY SYSTEMS DESIGNEDTO BRING PHARMACEUTICALLY USEFUL COMPOUNDS TO THE BRAIN PARENCHYMA. OBSERVED SPECIES DIFFERENCES IN BRAIN CAPILLARY ENDOTHELIAL CELLS-POTENTIAL TARGETS FOR DELIVERY MOLECULES ...

THIS SBIR PROPOSAL DISCUSSES THE DEVELOPMENT OF A THEORY OF TACTICAL DECISION MAKING EXPERTISE, BASED ON EXISTING LITERATURE AND INTERVIEWS WITH KEY MILITARY PERSONNEL. OUR CENTRAL THEORETICAL IDEA IS THAT EXPERT TACTICAL COMMANDERS HAVE A MENTAL MODEL OF THE BATTLE SITUATION THAT DIFFERS IN MEASURABLE WAYS FROM THAT OF NOVICES. WE SUGGEST THAT TRAINING AND EXPERIENCE FACTORS ENHANCE THE EXPERTISE ...