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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. PEDIATRIC BODY LEAD BURDEN BY X-RAY FLUORESCENCE

    SBC: ABIOMED, INC.            Topic: N/A

    THREE TO FOUR MILLION YOUNG CHILDREN FROM ALL LEVELS OF SOCIETY ARE EXPOSED TO ENVIRONMENTAL SOURCES OF LEAD AT CONCENTRATIONS THAT PLACE THEM AT RISK FOR ADVERSE HEALTH EFFECTS. YET, THERE IS NO TOOL AVAILABLE FOR MEASURING TOTAL PEDIATRIC BODY BURDEN OF LEAD. THIS PROJECT WILL DEVELOP AN X-RAY FLUORESCENCE (XRF) INSTRUMENT THAT WILL ALLOW MEASUREMENT OF BODY LEAD BURDEN IN CHILDREN IN VIVO AND N ...

    SBIR Phase II 1992 Department of Health and Human Services
  2. LONG-TERM CENTRIFUGAL VENTRICULAR ASSIST DEVICE

    SBC: ABIOMED, INC.            Topic: N/A

    CENTRIFUGAL BLOOD PUMPS HAVE BEEN USED EXTENSIVELY FOR SHORT-TERM CIRCULATORY ASSISTANCE AND PERFUSION PUMPS. THEIR UTILITY FOR LONG-TERM VENTRICULAR ASSISTANCE IS LIMITED BY THROMBUS FORMATION AT THE SHAFT SEAL. ABIOMED, INC., WILL DEVELOP A MAGNETICALLY SUSPENDED CENTRIFUGAL BLOOD PUMP THAT WILL HAVE NO SHAFT SEAL AND BE SUITABLE FOR LONG-TERM CIRCULATORY SUPPORT IN EITHER AN IMPLANTED OR EXTRAC ...

    SBIR Phase II 1992 Department of Health and Human Services
  3. AN OPTIMAL LASER SOURCE FOR SMALL-DIAMETER VASCULAR ANASTOMOSES

    SBC: ABIOMED, INC.            Topic: N/A

    THIS RESEARCH WILL DEMONSTRATE THAT A NEW 1.9-MU M LASER CAN PERFORM LASER-ASSISTED VASCULAR ANASTOMOSES OF SMALL-DIAMETER VESSELS (1 TO 5 MM). THE 1.9-MU M LIGHT HAS OPTIMAL ABSORPTION CHARACTERISTICS TO ENSURE AN EVEN DEPOSITION OF ENERGY IN THE VESSEL WALL. THIS SHOULD RESULTIN A MORE DESIRED TEMPERATURE PROFILE IN THE REGION OF THE ANASTOMOSIS WHEN COMPARED WITH ALTERNATIVE SOURCES. THE PROPOS ...

    SBIR Phase II 1992 Department of Health and Human Services
  4. A PERIODONTAL TEMPERATURE AND DEPTH PROBE

    SBC: ABIOMED, INC.            Topic: N/A

    THE OBJECTIVE IS TO DEVELOP A PERIODONTAL PROBE CAPABLE OF MEASURING SITE TEMPERATURE AND POCKET DEPTH SIMULTANEOUSLY AND AUTOMATICALLY. THE PROBE IS INTENDED TO BE A RAPID SCREENING DEVICE FOR THE STATE OF PERIODONTAL HEALTH DURING ROUTINE DENTAL EXAMINATIONS. STUDIES HAVE SHOWN THAT THE INFLAMED SULCUS IS ACCOMPANIED BY ELEVATED SITE TEMPERATURES. POCKET DEPTHS ARE ROUTINELY MEASURED DURING DENT ...

    SBIR Phase II 1992 Department of Health and Human Services
  5. True Three Dimension (3D) Display

    SBC: ACT Research Corporation            Topic: N/A

    We live in a three dimensional world, where we can go around an object and observe it from all angles. The current displays: TVs, movie screens, and computer monitors are all two dimensional devices. These displays give us only "flattened" realities. The missing third dimension carries with it tremendous amounts of information that is absolutely vital to the users. ACT has demonstrated the princip ...

    SBIR Phase I 1992 Department of DefenseMissile Defense Agency
  6. RADAR MULTIPATH AND CLUTTER SUPPRESSION IN THEATRE MISSILE DEFENSE

    SBC: ADCOM SYSTEMS TECHNOLOGY,INC.            Topic: N/A

    INNOVATIVE APPROACHES ARE PROPOSED FOR ANALYTICAL INVESTIGATION AND EVALUATION IN A PHASE I EFFORT TO DEVELOP MULTIPATH AND CLUTTER SUPPRESSION TECHNIQUES FOR LOW SURFACE GRAZING ANGLE CMW AND MMW RADAR DIRECT OR DIFFERENTIAL GUIDANCE OF A MISSILE TO A TARGET IN THEATER MISSILE DEFENSE APPLICATIONS. THE RADAR IS EITHER MISSILE-BONE OR SITUATED IN THE MISSILE LAUNCH AREA OR ON THE LAUNCH PLATFORM. ...

    SBIR Phase I 1992 Department of DefenseAir Force
  7. RADAR HIGH ANGLE RESOLUTION TECHNIQUES

    SBC: ADCOM SYSTEMS TECHNOLOGY,INC.            Topic: N/A

    1Innovative techniques for radar high angle resolution are proposed for investigation in a Phase I effort to enable the resolution of the direction of arrival (DOA) of returns from multiple targets that fall within one beamwidth and within the same range and Doppler Cells. The techniques proposed emphasize the pursuit for optimal utilization of available aperture space, by a combination of arrange ...

    SBIR Phase I 1992 Department of DefenseNavy
  8. HEPATIC DIRECTED ANTIVIRAL AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    THE OBJECT OF THIS RESEARCH IS TO DEVELOP AN ANTI-HEPATITIS B VIRUS PRO-DRUG WHICH WILL CONCENTRATE IN THE INFECTED LIVER TISSUE BY BINDING THE HEPATIC ASIALOGLYCOPROTEIN RECEPTOR AND RELEASING THE ACTIVE FORM OF THE DRUG IN THE HEPATOCYTE. TOWARD THIS END, A NUMBER OF ADENOSINE ARABINOFURANOSIDE/ARABINOGALACTAN CONJUGATES WILL BE SYNTHESIZED. THE CONJUGATES WILL BE EVALUATED AS SUITABLE PRODRUGS ...

    SBIR Phase I 1992 Department of Health and Human Services
  9. RECEPTOR DIRECTED SUPERPARAMAGNETIC MRI CONTRAST AGENTS

    SBC: ADVANCED MAGNETICS, INC.            Topic: N/A

    THE ULTIMATE GOAL OF THIS RESEARCH IS THE DEVELOPMENT OF TISSUE SPECIFIC, OR DIRECTED MAGNETIC RESONANCE UMAGING (MRI) CONTRAST AGENTS. THESE AGENTS WILL CONSIST OF PEPTIDES ATTACHED TO SMALL, BIODEGRADABLE SUPERPARAMAGNETIC IRON OXIDE COLLOIDS. THE BIODISTRIBUTION OF THE SUPERPARAMAGNETIC IRON OXIDE LABEL WILL BE DETERMINED BY THE PEPTIDE ON THE SURFACE OF THE IRON OXIDE AND BY THE PRESENCE OF SP ...

    SBIR Phase I 1992 Department of Health and Human Services
  10. STABILITY FORCE PLATFORM

    SBC: Advanced Mechanical Technology, Inc.            Topic: N/A

    MEASUREMENT OF POSTURAL SWAY IS NOW BEING USED TO INVESTIGATE THE EFFECTS OF DRUGS, TOXINS, AND AGING ON THE NEUROMUSCULAR SYSTEM OF HUMANS AND TO DEVISE STRATEGIES TO HELP ELDERLY INDIVIDUALS REDUCE THE RISK OF FALLING. ONE POPULAR METHOD OF MEASURING SWAY IS WITH A FORCE PLATFORM; HOWEVER, CURRENT FORCE PLATFORMS ARE DESIGNED FOR MORE DEMANDING APPLICATIONS THAN MONITORING HUMAN SWAY. IT IS PLAN ...

    SBIR Phase II 1992 Department of Health and Human Services

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