Award Data

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the development of a novel, bioactive polymer for use in ventricular assist devices (VAD), and other long-term blood contacting implantable devices. Although VADs are becoming an important therapeutic option for patients in heart failure, serious problems persist secondary to thromboembolic complications and continue t ...

DESCRIPTION (provided by applicant): The ultimate objective of this proposal is the commercialization of a pediatric ventricular assist device (VAD). Although, VADs, both implantable and paracorporeal, have become an important surgical option for adult patients with myocardial failure unresponsive to less aggressive therapy, no VADs are commercially available for short-term use in children or smal ...

This SBIR Phase II research project strives to develop an Advanced Ultrasonic Beamformer that is unparalleled in its scalability and signal processing features. The ultrasonic beamformer architecture will be unique in its breadth of features. The architecture was developed as the superset of features across several fields including medical imaging, medical therapy, bone density measurement, vascul ...

The Phraselator, a handheld automatic translation device, currently uses a cardioic microphone as an input for automatic speech recognition (ASR). This microphone is highly vulnerable to performance degradation in typical noisy military environments and,thus, there is a need for an improved transducer for this application. We propose to develop a new directional microphone that is immune to extr ...

As the unmanned exploration of Mars and Venus becomes more of a focus area at NASA, inflatable, rigidizable wings will become an enabling technology. The successful development of this type of wing will also have significant military applications. The utility of unmanned aerial vehicles (UAVs) for the military has been dramatically demonstrated in the conflict in Afghanistan. Rigidization of infla ...

This Small Business Innovation Research (SBIR) Phase I project will develop a prepreg material that, while maintaining the advantages of a powder towpreg system, will eliminate the use of high price, finely ground powders. By generating fine particles in situ using aerosol formation from molten polymers two steps will be eliminated from the manufacturing process -- powder grinding and powder sin ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Although weight loss is the most effective treatment for type 2 diabetes, current methods for reducing weight typically are insufficient for long-term weight loss. The mission of AdipoGenix, Inc. is to discover, develop and license novel the ...

DESCRIPTION (provided by applicant): Obesity is a well-established risk factor for a number of diseases, including type 2 diabetes and coronary heart disease. Existing drug and dietary treatments for obesity are only modestly effective. An approach that is very likely to be effective in treating obesity and with a good side effect profile is a drug that acts directly on lipid metabolism in the fat ...

R3 Logic proposes to develop an openly accessible Design Environment that will incorporate CAD tools needed for the analysis and design of 3D integrated circuits, including schematic capture, VHDL interfaces, 3D physical layout, verification, 3D parasiticextraction, interactive coupled electro-thermal simulations, and thermally-aware place and route methods. We will achieve this goal, first by bui ...

The objective of this effort is to create an innovative bioinformatics platform for microarray data management and analysis. This platform will overcome the following limitations inherent in current microarray systems: (1) current systems typically do notaddress all types of array data, (2) current systems do not record the context of the samples, which hinders scientific and statistically relevan ...