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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. A Novel Polymeric Trileaflet Heart Valve Prosthesis

    SBC: ABIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to produce a fully characterized polyurethane heart valve prosthesis that will be ready for clinical evaluation. Existing replacement valves suffer from several shortcomings. Specifically, biological tissue fixation and methods used to mount the tissue to the supporting stent of bioprostheses cause time dependent structural changes ...

    SBIR Phase II 2007 Department of Health and Human Services
  2. BIOACTIVE POLYMER FOR VENTRICULAR ASSIST DEVICES- SBIR TOPIC #37

    SBC: ABIOMED, INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  3. Marine Portable Power Unit

    SBC: Atrex Energy, Inc.            Topic: N06105

    Many military missions involve the use of equipment that requires small batteries for power where AC grid power is unavailable. Also, there is a need for a high quality power output device that conditions a power input to make it suitable to power sensitive communications equipment. The weight of this equipment is also a factor which affects Its usefullness in quick moving military situations. M ...

    SBIR Phase I 2007 Department of DefenseNavy
  4. High Efficiency Regenerative Helium Compressor

    SBC: Advanced Mechanical Technology, Inc.            Topic: X901

    Helium plays several critical rolls in spacecraft propulsion. High pressure helium is commonly used to pressurize propellant fuel tanks. Helium cryocoolers can be used to sub-cool and thereby densify cryogenic propellants such as liquid hydrogen (LH2) and liquid oxygen (LO2). The use of densified cryogenic propellants can reduce the gross payload weight of a launch vehicle by up to 20%, or incr ...

    SBIR Phase I 2007 National Aeronautics and Space Administration
  5. SBIR Phase II: Low Cost Pressure Infiltration Casting Process to Support High Volume Manufacture of Graphite-Metal Thermal Management Components

    SBC: ADVANCED THERMAL TECHNOLOGIES            Topic: MI

    The Small Business Innovation Research (SBIR) Phase II project seeks to develop the use of a gas pressure infiltration casting process to manufacture graphite-metal billet materials that would be used to produce components for high power electronic device packaging. The heat dissipation rate of electronic devices has increased dramatically as a result of advances in semiconductor materials, faste ...

    SBIR Phase II 2007 National Science Foundation
  6. SBIR Phase I: Low-Cost Hot Press Die Casting of Graphite-Metal Materials

    SBC: ADVANCED THERMAL TECHNOLOGIES            Topic: MI

    The Small Business Innovation Research (SBIR) Phase I project will develop a hot press die casting technology to be used in the production of graphite-metal materials. In the proposed work, graphite preform and metal will be placed in a multi-chamber graphite die set and loaded into a hot press. Following evacuation of the die set and heating to the desired melt temperature, the die set mold wit ...

    SBIR Phase I 2007 National Science Foundation
  7. Improved system for producing adenoviral vectors

    SBC: ADVANTAGENE, INC            Topic: N/A

    First generation non-replicative adenoviral vectors show promise as anti-cancer agents and as prophylactic vaccines. Current methods for manufacturing these vectors use either the 293 cell line or the PER.C6 cell line. These producer cells provide complementary E1a and E1b viral function in the cell for disabled adenoviral vectors. The 293 cell line has been very useful and widely used for mak ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Clinical and Immunologic Evaluation of ProstAtak for Prostate Cancer

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to develop a new therapeutic to improve the outcome for patients with intermediate-risk prostate cancer. The indication is a first-line adjuvant to be combined with radiation therap y for prostate cancer. The desired outcomes are improved local control rate, decreased recurrence and improved disease-free survival. This gran ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Clinical study of AdV-tk radiogenetherapy for malignant*

    SBC: ADVANTAGENE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Malignant gliomas have a very poor prognosis with median survival measured in months rather than years. It is a disease with great need of novel therapeutic approaches. Within cancer gene therapy the use of adenoviral vectors to deliver HSV-tk (AdV-tk) has been one of the most widely studied and promising approaches. A few dose escalation Phase I studies ha ...

    SBIR Phase II 2007 Department of Health and Human Services
  10. Heterogeneous CB Sensor Network Modeling Tool

    SBC: ATMOSPHERIC & ENVIRONMENTAL RESEARCH, INC.            Topic: CBD07108

    While individual instances of Chemical/Biological (CB) detection sensor technology development have progressed steadily, deficiencies remain. An integrated multi-sensor network for CB detection is a promising concept for improving performance. New development is needed to address the complex challenge of how to optimally deploy and evaluate CB sensor networks to ensure maximum utility against an e ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense

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