Award Data

DESCRIPTION (provided by applicant): The objective of this proposal is to develop a less invasive long-term copulsation device to treat patients in late Class III and early Class IV stages of heart failure (HF). Chronic congestive heart failure is the largest unsolved problem in cardiac care today. There are over 5.5 million people in the United States with this diagnosis and the number of patient ...

DESCRIPTION (provided by applicant): The objective of this SBIR program is the modification of a polymeric trileaflet heart valve to a valve prosthesis that can be delivered percutaneously as a transcatheter aortic valve replacement. Key innovations include improved durability and hemodynamic properties, lower manufacturing costs, and simplified delivery over existing transcatheter bioprosthetic v ...

DESCRIPTION (provided by applicant): The overall objective of this proposed program is the commercialization of the Pediatric Impella system, a minimally invasive ventricular assist device (VAD) for treatment of acute heart failure in pediatric patients. The device will be a less traumatic alternative to extracorporeal membrane oxygenation (ECMO), the current standard of care for these patients. T ...

DESCRIPTION (provided by applicant): An estimated 1.6 million head injury occurs every year in the United States. Traumatic brain injury affects 3 out of every 1000 Americans each year accounting for as many as 60,000 deaths and an estimated 70,000 to 90,000 patients with permanent neurologic disabilities. Despite advances in the treatment of patients with head injuries, traumatic brain injury ...

DESCRIPTION (provided by applicant): The goal of this SBIR Phase 2 application is to continue the development and evaluation the intrathoracic pressure regulator (ITPR), intended to increase circulation and blood pressure clinically significant states of hypotension, including cardiac arrest and septic shock. This novel non-invasive device is inserted within a standard respiratory circuit between ...

According to existing data, there are more than 1.5 million of Americans sustaining a Traumatic Brain Injury (TBI) each Year. Balance disorders represent one of the main regular problems that patients have to deal with, and thus everyday. Rehabilitation programs do exist but they are dependable of the clinician or physiotherapist and they do not take in account the multimodal aspects of balance co ...

Cooking appliances in U.S. Army field kitchens are currently heated by burning JP-8 fuel using electrically powered burners. Power is supplied by a separate JP-8 fired generator that serves multiple appliances simultaneously. This is inefficient, as generators are only 20-25% efficient, and unreliable since failure of the generator results in the failure of the entire kitchen operation. This is a ...

DESCRIPTION (provided by applicant): This work is focused on exploring the physiological processes and therapies associated with hot flashes. The project proposes to develop a tool for use by researchers studying hot flashes in broad population research studies. Hot flashes are experienced by approximately 80 percent of American women between the ages of 45 and 54 and are a significant concern dur ...

DESCRIPTION (provided by applicant): Project Summary/Abstract This project will improve the energy efficiency of home oxygen concentrators for patients on long-term oxygen therapy (LTOT) and save energy costs for the patients. The number of patients on LTOT is estimated to be 1.2 million. The cost of electricity can vary from one region, to another so it is difficult to determine the exact monthly ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics Corporation (AME) proposes to develop and deploy a smartphone-based health-coaching tool, which we will specifically design for people with Chronic Obstructive Pulmonary Disease (COPD). Regular spontaneous physical activity plays a large role in maintaining health, including for patients with COPD. This tool consists of a smartphone ...