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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A Bioactive Nanofibrous Sewing Cuff for Treatment of Cardiac Valvular Disease

    SBC: BIOSURFACES, INC.            Topic: NHLBI

    PROJECT SUMMARY Cardiac valve repair or replacement is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting cardiac output. Both procedures require the use of a woven or knitted polyester material with an internal reinforcement (Teflon, silicone or metal) to either stabilize the native valve (annuloplasty r ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. A Biological Small Angle X-ray Scattering Station (BioSAXS) for the Compact Light

    SBC: LYNCEAN TECHNOLOGIES, INC.            Topic: NIGMS

    7. Project Summary/Abstract We propose to develop a Biological Small-angle X-ray Scattering (BioSAXS) station for the Compact Light Source, a powerful new generation of X-ray sources, which will enable biologists and biochemists to pursue state-of-the-artresearch in macromolecular structure studies in their own laboratories. The frontier of structural biology is the determination of large macromol ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Abuse Tolerant High Energy LiCoPO4-Based 5V Li-ion Cells

    SBC: TIAX LLC            Topic: A14023

    TIAX will build, characterize and abuse test lithium-ion cells employing LiCoPO4 cathodes and control metal-oxide based cathodes (such as LiCoO2 ) opposite graphite anodes. In Phase I, TIAX will perform overcharge and external short circuit tests to the specification of the UL1642 standard and will also perform nail penetration tests on both types of cells. In the option program TIAX will perfor ...

    SBIR Phase I 2014 Department of DefenseArmy
  4. Accelerating Wound Healing through RNAi

    SBC: Somagenics, Inc.            Topic: 300

    DESCRIPTION provided by applicant The growing populations of the elderly and those with type II diabetes are at high risk for developing chronic wounds that are slow to heal Effective therapeutics to promote wound healing could significantly improve the lives of these people Normal wound healing involves a coordinated cascade of events that are stimulated in part by the hypoxia that results f ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Accessible Balance and Falls Prevention Exercise Tool Across the Continuum of Car

    SBC: BLUE MARBLE REHAB INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Objective: This Phase 1 SBIR proposes to optimize the interface and interaction of a digital translation of Evidence Based Falls Prevention programs for use across the continuum of care and community living that affordseasy adoption, adherence and monitoring of falls prevention exercises for all stakeholders including those with limited technical experience. Pu ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Accurate Angle of Incidence (AOI) Measurement Capability

    SBC: TOYON RESEARCH CORPORATION            Topic: AF131177

    ABSTRACT: For certain weapons systems, lethality is directly correlated to the orientation of the weapon with respect to the target at impact, also known as the angle of incidence (AOI). Accurately measuring AOI is of the utmost importance in developing and advancing state-of-the-art precision weapon systems. Currently, there is no commercially available sensor system for measuring AOI to the pre ...

    SBIR Phase I 2014 Department of DefenseAir Force
  7. A Cell-Penetrating Anthrax Antitoxin

    SBC: PLANET BIOTECHNOLOGY, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this research is to develop an economical, safe, effective therapy to reverse the activity of the catalytic component, LF, of the Bacillus anthracis toxin (lethal toxin), within the cytoplasm of the intoxicated cell. Success in achieving this goal will lead to better outcomes than currently seen with antibiotics or antitoxins like raxibacumab or PB ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. ACLAMATE: Automated Cognitive Load Assessment for Medical StAff Training and Evaluation

    SBC: Aptima, Inc.            Topic: DHP13002

    Although great strides have been made in the development of simulators for training technical and teamwork skills, much less progress has been made with regard to skill assessment. Typically, performance is measured using a rating scale with anchors ranging from"low"to"high."Such methods are too coarse to provide an accurate assessment of individual or team performance. What is needed are unobtrus ...

    SBIR Phase I 2014 Department of DefenseDefense Health Program
  9. A Combination Therapy Approach to Treating Drug Resistant Fungal Infections

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Despite the introduction of newer triazoles and echinocandins invasive fungal infections IFIandapos s including invasive candidiasis IC remain very difficult to treat with currently available antifungals The annual cost burden of treating nosocomial fungal infections exceeds $ billion a year in the United States alone Worldwide the annual incidence o ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Compact, High-power Terahertz Amplifier for DNP-NMR and EPR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): We propose to develop a compact, cost-effective Traveling Wave Tube (TWT) amplifier at 263 GHz with 50 W of peak power, 5 W of continuous wave power and 5% instantaneous bandwidth for application in Dynamic Nuclear Polarization (DNP) enhanced solid-state and solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy. With DNP, the inherently smal ...

    SBIR Phase I 2014 Department of Health and Human Services
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