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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Bioactive Nanofibrous Sewing Cuff for Treatment of Cardiac Valvular Disease
SBC: BIOSURFACES INC Topic: NHLBIPROJECT SUMMARY Cardiac valve repair or replacement is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting cardiac output. Both procedures require the use of a woven or knitted polyester material with an internal reinforcement (Teflon, silicone or metal) to either stabilize the native valve (annuloplasty r ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Biological Small Angle X-ray Scattering Station (BioSAXS) for the Compact Light
SBC: LYNCEAN TECHNOLOGIES, INC. Topic: NIGMS7. Project Summary/Abstract We propose to develop a Biological Small-angle X-ray Scattering (BioSAXS) station for the Compact Light Source, a powerful new generation of X-ray sources, which will enable biologists and biochemists to pursue state-of-the-artresearch in macromolecular structure studies in their own laboratories. The frontier of structural biology is the determination of large macromol ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Accelerating Multi-modal Biomarker Discovery in Translational Research with Cloud Data Integration
SBC: CYTOBANK, INC. Topic: 400Project Summary Abstract Cytobank is the leading cloud based platform for analysis and storage of single cell flow and mass cytometry datatechnologies that are essential for investigating the interplay between the immune system and disease conditions including cancerThere are numerous data analysis steps between raw data and insight especially for many single cell technologieswhere the data analys ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Accelerating Wound Healing through RNAi
SBC: Somagenics, Inc. Topic: 300DESCRIPTION provided by applicant The growing populations of the elderly and those with type II diabetes are at high risk for developing chronic wounds that are slow to heal Effective therapeutics to promote wound healing could significantly improve the lives of these people Normal wound healing involves a coordinated cascade of events that are stimulated in part by the hypoxia that results f ...
SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Accessible Balance and Falls Prevention Exercise Tool Across the Continuum of Car
SBC: BLUE MARBLE REHAB INC Topic: NIADESCRIPTION (provided by applicant): Objective: This Phase 1 SBIR proposes to optimize the interface and interaction of a digital translation of Evidence Based Falls Prevention programs for use across the continuum of care and community living that affordseasy adoption, adherence and monitoring of falls prevention exercises for all stakeholders including those with limited technical experience. Pu ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Cell-Penetrating Anthrax Antitoxin
SBC: PLANET BIOTECHNOLOGY, INC. Topic: NIAIDDESCRIPTION (provided by applicant): The goal of this research is to develop an economical, safe, effective therapy to reverse the activity of the catalytic component, LF, of the Bacillus anthracis toxin (lethal toxin), within the cytoplasm of the intoxicated cell. Success in achieving this goal will lead to better outcomes than currently seen with antibiotics or antitoxins like raxibacumab or PB ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Circulating Biomarker for use in Monitoring Metastatic Breast Cancer
SBC: A&G PHARMACEUTICAL, INC. Topic: 102Cost-effective and minimally invasive monitoring of metastatic breast cancer (MBC) patients for disease progression or response to therapy is an unmet need in the clinical management of the disease. Imaging technologies are currently the gold standard of such monitoring. However, there is controversy regarding the type and frequency of imaging required. Imaging is expensive, time consuming, slow t ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions
SBC: Spire, Inc. Topic: NIDAPROJECT SUMMARY Recovery from substance use disorders (SUDs) is greatly impacted by the cognitive and emotional state of the individual, and learning new thought and behavioral patterns can facilitate successful treatment and recovery. Specifically, fluctuations in stress or anxiety can trigger lapses to drug use. Even when actual use is avoided, stress-induced craving is likely to be distracting ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Combination Therapy Approach to Treating Drug Resistant Fungal Infections
SBC: Amplyx Pharmaceuticals, Inc. Topic: NIAIDDESCRIPTION provided by applicant Despite the introduction of newer triazoles and echinocandins invasive fungal infections IFIandapos s including invasive candidiasis IC remain very difficult to treat with currently available antifungals The annual cost burden of treating nosocomial fungal infections exceeds $ billion a year in the United States alone Worldwide the annual incidence o ...
SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
A Compact, High-power Terahertz Amplifier for DNP-NMR and EPR Spectroscopy
SBC: BRIDGE 12 TECHNOLOGIES, INC. Topic: NIGMSDESCRIPTION (provided by applicant): We propose to develop a compact, cost-effective Traveling Wave Tube (TWT) amplifier at 263 GHz with 50 W of peak power, 5 W of continuous wave power and 5% instantaneous bandwidth for application in Dynamic Nuclear Polarization (DNP) enhanced solid-state and solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy. With DNP, the inherently smal ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health