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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. DMX: Enabling Blind Source Separation for Hearing Health Care

    SBC: SPEECH TECHNOLOGY/APPLIED RESEARCH CORP.            Topic: NIDCD

    DESCRIPTION provided by applicant Typical biological environments comprise complex mixtures of signals from multiple biological and environmental sources Some sources contain critical information that researchers seek to acquire other sources are distractions that interfer with data acquisition Common acoustic environments are an important example a significant segment of the aging US popul ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Serum Hepcidin Immunoassay: Laboratory to Marketplace

    SBC: INTRINSIC LIFESCIENCES LLC            Topic: 300

    DESCRIPTION provided by applicant Disorders of iron metabolism are among the most common human diseases During the last decade rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders The peptide hormone hepcidin has emerged as the master regulator of iron metabolism Dysregulation of hepcidin is the principal or contributing factor in most syst ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. SAMBA HIV-1 Semi-quantitative Test for resource limited settings

    SBC: DIAGNOSTICS FOR THE REAL WORLD LIMITED            Topic: R

    DESCRIPTION provided by applicant SAMBA HIV Semi quantitative Test for resource limited settings Project Abstract The ultimate aim of this project is to develop a CE marked and or FDA approved diagnostic platform for viral load monitoring of HIV infected patients in point of care POC and resource limited settings Currently available viral load tests are not suitable for such settings du ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Sample Pretreatment for Human Fluids

    SBC: Sonata Biosciences Inc            Topic: 400

    DESCRIPTION provided by applicant In this proposal we seek to develop a new method and instrument to reduce the complexity of protein mixtures derived from human fluids with an eye to discovery of very low abundance protein biomarkers The proposed method accomplishes two tasks it reduces the dynamic range of the protein mixture by three or more orders of magnitude and it concentrates proteins ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Applications

    SBC: EYENUK, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant In this small business innovations research SBIR project we present EyeArt a retinal image analysis tool for automated diabetic retinopathy DR screenings with high diag nostic efficacy With its interface to EyePACS a license free scalable telemedicine plat form EyeArt will aid the expansion of DR screening and help bridge the exponentially growing di ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. MicroRNA-Based Radiation Biodosimeter (MiRAD)

    SBC: Chromologic LLC            Topic: NIAID

    DESCRIPTION provided by applicant The broad long term goal of this project is to develop an optically based radiation biodosimeter that rapidly minutes measures changes in serological microRNA miRNA biomarkers to predict acute radiation syndrome ARS MicroRNAs miRNAs are short base non coding RNA strands that control a host of biological processes through regulation of pr ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Rapid and On-site Monitoring of Urinary Arsenic Metabolites

    SBC: Giner, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Giner Inc proposes a portable inexpensive and rapid response monitor for arsenic speciation in urine Arsenic species excreted in urine are reflective of exposure to toxic arsenic species and therefore this monitor will be a valuable tool in medical diagnostics and epidemiological studies by allowing determination of arsenic exposure by a technique that is ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Device for Measuring Capillary Blood Flow and the Onset of Shock

    SBC: Radiation Monitoring Devices, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Hemorrhagic shock is a major cause of death in emergency departments and trauma centers Currently there is no clinically accepted quantitative monitor of the onset of hemorrhagic shock Death from hemorrhagic shock results from diminished capillary blood flow and the resultant failure of the body to oxygenate major organs The long term goal of this proposal ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Flavivirus Antivirals Targeting Dengue Virus and WNV Protease

    SBC: CALASIA PHARMACEUTICALS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Mosquito borne members of the Flavivirus family include four serotypes of dengue virus DENV and West Nile Virus WNV and are classified as re emerging pathogens due to the frequency and severity of recent epidemics There are an estimated million DENV infections reported each year resulting in nearly deaths More than billion people are at ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Novel Inhibitors Targeting Early Steps of Human Cytomegalovirus Replication

    SBC: MICROBIOTIX, INC.            Topic: R

    DESCRIPTION provided by applicant Human cytomegalovirus HCMV infection is a major cause of morbidity and mortality in immunosuppressed patients especially recipients of solid organ or bone marrow transplants HCMV infection of neonates is associated with deafness mental retardation and mortality Although five anti viral drugs GCV val GCV CDV PFA Foscarnet have been approved and lice ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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