List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Combination Therapy Approach to Treating Drug Resistant Fungal Infections

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Despite the introduction of newer triazoles and echinocandins invasive fungal infections IFIandapos s including invasive candidiasis IC remain very difficult to treat with currently available antifungals The annual cost burden of treating nosocomial fungal infections exceeds $ billion a year in the United States alone Worldwide the annual incidence o ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Computer Modeling Approach

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: 101

    DESCRIPTION Cryptococcal meningitis CM continues to be a significant cause of mortality among HIV positive individuals and a major worldwide health concern The estimated mortality rate for HIV infected acute CM patients is within months after infection in North America despite patient access to good health care resources In sub Saharan Africa alone the effects of CM are devastating ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A human monoclonal for RSV prophylaxis

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Respiratory syncytial virus RSV is the leading cause of lower respiratory tract illness in infants and young children worldwide In premature neonates RSV infection results in high levels of morbidity and mortality In the United States alone there are more than hospitalizations and deaths per year attributable to RSV The only prophylaxis for R ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A molecular barcoding sequencing kit for highly efficient and accurate single cel

    SBC: CELLULAR RESEARCH, INC.            Topic: 172

    DESCRIPTION provided by applicant We propose to develop and commercialize high sensitivity and accuracy RNA sequencing kits suitable for gene expression measurements in limiting input samples such as single cells During Phase I we proposed the concept of using molecular barcodes in the form of DNA sequence tags to label individual molecules or copies of RNA for gene expression analysis in ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A MULTIPLEXED REMOTE SYSTEM FOR FILOVIRUS DISEASE SURVEILLANCE

    SBC: Cellmic, LLC            Topic: NIAID

    Proposes an advanced Ebola and Marburg disease telemonitoring and assessment platform that will enable the digital modernization of point of care diagnosticsdisease surveillanceand healthcare screening by minimally trained personnel at the point of careOffering a complete diagnostics solutionthe platform includes a microfluidics assay for the detection of infections caused by Ebola and Marburg fil ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Music-Based Rehabilitation Device for Training and Assessing Hand Function

    SBC: FLINT REHABILITATION DEVICES, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Hand impairment is a common condition that contributes substantially to disability in the U S and around the world In the case of stroke alone it is estimated that of the individuals who survive a stroke each year require hand therapy Intensive rehabilitation exercise reduces long term hand impairment Unfortunately as soon as weeks after th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. A Rewards Program Contributing to Healthier Eating in Restaurants & Schools

    SBC: ACCENTS ON HEALTH, INC.            Topic: 102

    DESCRIPTION provided by applicant This research will expand implement and evaluate a restaurant based incentive program that provides funding to schools to support school Wellness Initiatives such as physical activity nutrition education and healthier lunch programs while encouraging and rewarding healthy eating behaviors in restaurants at the same time This project represents the first s ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Accelerating Wound Healing through RNAi

    SBC: Somagenics, Inc.            Topic: 300

    DESCRIPTION provided by applicant The growing populations of the elderly and those with type II diabetes are at high risk for developing chronic wounds that are slow to heal Effective therapeutics to promote wound healing could significantly improve the lives of these people Normal wound healing involves a coordinated cascade of events that are stimulated in part by the hypoxia that results f ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. AD-MS Chips for Biofluids-Based Diagnosis of Alzheimer's Disease

    SBC: Newomics Inc            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is a devastating neurodegenerative disease that affects more than million people including million Americans worldwide and this number is expected to reach more than million by the year Recent disappointing clinical trials of bapineuzumab and solanezumab in AD treatment further aggravate the problem There is cu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Adjuvant Development for a Thermostable Respiratory Influenza Vaccine

    SBC: UNIVERSAL STABILIZATION TECHNOLOGIES, INC            Topic: NIAID

    The objective of the proposed project is evaluation of two novel non aluminum vaccine adjuvantsCpG ODN and AdVaxinulin polysaccharidewith intranasal delivery of thermostable live attenuated influenza vaccineLAIVand irradiation inactivation inactivated influenza vaccineIr IIVpowdersThe proposal aims to formulate thermostable vaccines in the dry powder format using patented Preservation by Vaporizat ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government