Award Data

PROJECT SUMMARY / ABSTRACTThe objective of this Phase II proposal is to further develop a novel device for ocular anesthesia based on thermo-electric cooling. Intravitreal injection therapy (IVT) is one of the most commonly performed procedures in all of medicine, with approximately 7 million injections in the USA in 2016. Ocular anesthesia is required, both for patient safety and for tolerability ...

Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technolo ...

Project Summary/Abstract Prospective evaluation of a surgical solution for breast cancer-associated lymphedema The proposed project will complete remaining key research and technology requirements that are needed to commercialize a ground-breaking interventional device for treating secondary lymphedema -- a chronic and debilitating disease that currently has no cure and impacts an estimated 15-30% ...

Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) 3/19/2018 Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) will be a tool that allows users to easily generate a wide range of data visualizations from the Fatality Analysis Reporting System (FARS). CONNECT will leverage open-source visual ...

Deep Learning-based Vehicle Tracking with Multiple Sensors 3/19/2018 The DOT is seeking an integrated unit that is capable of identifying and tracking individual vehicles with high accuracy using multiple vehicle detection inputs, including video images, radar-based detection, and wireless signal inputs (including DSRC, cellular, Wi-Fi, and Bluetooth signals), with a deep learning-based engine ...

Digital Twins for Bridge Management through the Integrating of Computer Vision and Finite Element Models 3/19/2018 We propose the development of an innovative integrated solution for health monitoring of bridge structures using a non-contact image-based measurement methodology. High-resolution and regular camera systems will be used to capture the bridge movements and the traffic passing the b ...

Proposal title: Detection of THC Use in Drivers The overall objective of this program is to develop a portable, cost-effective and non-invasive sensor device for near real-time salivary THC detection to be used at roadside in drivers. This will eliminate the need for expensive and time-consuming analytical techniques which have a turn-around time of several days. During the Phase I program Giner ...

Proposal title: A Robust Railway Track Crack Detection System Using Thermal Signatures In Phase I, we developed a practical sensor platform suitable for mounting on the back of train. A large amount of IR images associated with rail tracks were collected on an MBTA train. Algorithms were developed to identify both right and left tracks from a moving train. To help detect track cracks, we develope ...

Proposal title: Detection of THC Use in Drivers The intoxicating effects of marijuana are of concern to the law enforcement community as well as to the general manufacturing, service and commerce community where employees may need to be screened for intoxication. A reliable method to quantitatively measure the amount of the intoxicating agent delta-9- tetrahydrocannabinol (THC) in suspected marij ...

Advances in clinical research have yielded many evidence-based guidelines to help clinicians provide the right care for the right patient at the right time; however, studies suggest that nearly half the time, that care does not reach the patient. Clinical decision support (CDS) is an information technology-enabled method to identify missed opportunities and optimize care. This proposal seeks to sy ...