Award Data

PROJECT SUMMARY / ABSTRACTThe objective of this Phase II proposal is to further develop a novel device for ocular anesthesia based on thermo-electric cooling. Intravitreal injection therapy (IVT) is one of the most commonly performed procedures in all of medicine, with approximately 7 million injections in the USA in 2016. Ocular anesthesia is required, both for patient safety and for tolerability ...

Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technolo ...

Project Summary/Abstract Prospective evaluation of a surgical solution for breast cancer-associated lymphedema The proposed project will complete remaining key research and technology requirements that are needed to commercialize a ground-breaking interventional device for treating secondary lymphedema -- a chronic and debilitating disease that currently has no cure and impacts an estimated 15-30% ...

This SBIR Phase I project aims to further the development a novel nanoparticle-based synthetic platelet technology for the treatment of internal, non-compressible hemorrhage after traumatic injury. Trauma is the leading killer of people aged 1-46, and uncontrollable hemorrhage after injury is the cause of 35% of pre-hospital trauma deaths and 90% of military combat casualties. This is because ther ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to reduce the power consumption of display and lighting products by 90%. It will do so by enabling the pervasive use of light emitting diodes (LEDs) in such products. LEDs consume substantially less power than other display/lighting technologies and also offer benefits such as superior pic ...

The broader impact/commercial potential of this project is to enable the automatic analysis of human motion using visual information gathered at high frequency. Within the manufacturing context?which represents 11% of US GDP [Bureau of Economic Analysis]?the collection and interpretation of this new set of large-scale time-and-motion data enables dramatic improvements in the understanding of assem ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a substantial reduction of leakage in high-density polyethylene (HDPE) pipes. HDPE is a type of plastic commonly used for water, oil, and gas distribution pipe systems. Billions of gallons of treated water are lost daily across the US due to leaking pipes, resulting in massive revenue loss, ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is in enabling additional energy savings in buildings by harvesting natural daylight and using it for illuminating the interior space with high efficiency and without glare, thus offsetting the need for electrical lighting. This will make building operations more sustainable and help improve t ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project achieves a widespread earthquake sensor network in the earthquake-prone regions. With this wide prevalence of the sensor network, this smart, real-time earthquake detection system can detect an earthquake within a second near an epicenter and notify the other users away from the epicenter befo ...

The broader impact/commercial potential of this project is that it will enable the automated harvesting of fragile produce such as strawberries to help offset a shrinking workforce and increased labor costs. The world population is expected to grow from 7.3 billion to 11.2 billion by 2100, this population growth and a rising middle class will place more demand on the agricultural industry. Present ...