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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Small Molecule Treatments to Enhance Neurological Recovery After Stroke
SBC: Stemetix, Inc. Topic: NINDSPROJECT SUMMARYStroke is a major public health problem in the U Sand worldwideIt is defined as an area of brain damagegenerally due to the sudden occlusion of an artery in or leading to the brainStroke can cause weaknessnumbnessvisual disturbancespeech difficultybalance problemsand memory lossamong other symptomsWhile good treatments exist to limit stroke in the first few hours after occurrencefew ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Prehospital and Emergency Room Stroke Diagnosis Using Quantitative Cerebral Hemodynamics
SBC: Neural Analytics, Inc. Topic: NINDSLarge vessel acute ischemic strokeAISis the leading cause of disability and fourth leading cause of death with approximatelyper year in the United States aloneAlthough treatments including interventionalstentrieverand pharmaceuticaltPAexist for large vessel occlusionLVOthere is not a rapid prehospital tool for diagnoses which guides the use of the correct therapyBecause the time to treatment for s ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina
SBC: PHYSICAL SCIENCES INC. Topic: NEIProject Summary Abstract Physical Sciences IncPSIis continuing the pursuit of new clinical applications and advanced multimodal capabilities for its novel retinal imaging technology based on an adaptive optics line scanning ophthalmoscopeAO LSOThe Compact Adaptive Optics Retinal ImagerCAORIeliminates high speed scanning componentsreduces the clinical footprint compared to research adaptive optics ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions
SBC: Spire, Inc. Topic: NIDAPROJECT SUMMARY Recovery from substance use disorders (SUDs) is greatly impacted by the cognitive and emotional state of the individual, and learning new thought and behavioral patterns can facilitate successful treatment and recovery. Specifically, fluctuations in stress or anxiety can trigger lapses to drug use. Even when actual use is avoided, stress-induced craving is likely to be distracting ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Therapeutic that Harnesses MIcrotubules to Enhance Corneal Wound Healing Following an Alkaline Burn
SBC: MICROCURES INC Topic: NEIThe cornea is one of the most important tissues in the eye and its transparency is critical for good visual function in humansCorneal tissue injuries are the most common everyday issue for practicing ophthalmologists and can run the gamut in severityIn severe modelssuch as corneal alkaline burnsextensive healing is needed and often the burn victim is left with reduced visual acuityHealing of large ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction
SBC: ANAGIN Topic: 103Abstract This application, “Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein- protein interaction,” addresses the critical need for more effective medications to treat chronic neuropathic pain affecting ~116 million people in the United States. Current pain medications such as NSAIDS, steroids, opiates and gabapentin analogs have documented and often severe sid ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel, Low-Cost Device to Guide Peripherally Inserted Central Catheter (PICC) Line Placement
SBC: Theranova LLC Topic: NIAAbstract Improper placement of peripherally inserted central cathetersPICCsis costly and has serious complications for critically ill patientsMore than one million PICCs are placed each year to provide IV therapieswhere navigation through the venous system is typically performed blindor without navigation guidanceAs a resultof PICC tips are not optimally placed on the first attempt and require rep ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A therapeutic approach for potential prevention of aromatase inhibitor-induced bone loss
SBC: NANOMEDIC INC Topic: NIAAbstractIn this SBIR Phase I applicationour goal is to demonstrate proof of concept of our lead chelating agent as a potential therapeutic for the prevention of osteoporosis induced by aromatase inhibitorAItherapy in postmenopausal women with hormone receptor positive breast cancerAlthough AI therapy shows great improvements in cancer free and overall survivalits treated patients face a risk of os ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A technology solution for peer-led Seeking Safety
SBC: LMN CONSULTING Topic: NIDAAbstractPeers are increasingly recognized as an important asset in healthcarePeer support is historically most prominent for substance use disorderSUDsuch as the world wide model of Alcoholics Anonymous and otherstep groupsYet for trauma and posttraumatic stress disorderPTSDthere have been few attempts at peer helpA major challenge of trauma peer groups is that they usually focus on telling the st ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Development of Oxy200 for the Treatment of Osteoporosis
SBC: Max Biopharma, Inc. Topic: NIAABSTRACT Osteoporosis directly affectsmillion Americans and anothermillion are osteopenic and at risk for developing osteoporosisPostmenopausal osteoporosis is most commonbut osteoporosis does also frequently affect older menAt MAX BioPharmawe are developing new and improved therapies for osteoporosis that aim to rebalance both bone formation and resorption based on a dual therapy approachBisphosp ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health