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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

Displaying 1 - 10 of 5001 results
  1. Feasibility study of a novel noninvasive RF sensor for blood pressure measurements.

    SBC: Blumio, Inc.            Topic: NCCDPHP

    PROJECT SUMMARYABSTRACTHigh blood pressureor hypertensionis an important public health challenge because of its high prevalence and its role in increasing risk for a variety of other diseasesAccording to the American Heart Associationapproximatelyout of everyadults in the United States has hypertensionand the situation is projected to worsen with the percentage rising to approximatelyof the adult ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. MicroRNA-based Radiation Biodosimeter (MiRAD) Phase II

    SBC: Chromologic LLC            Topic: NIAID

    Abstract In response to PAthe broad long term goal of this project is to develop a portable radiation biodosimeter to be used at the point of carePOCfor assessing precise radiation exposure and susceptibility for acute radiation syndromeARSwithin the firstdays of exposure starting withL of blood collected from a finger stick and a turnaround timeTATof less thanminutesThe device measures changes in ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. NNCI Synapse: Development of a Mobile Application to Disseminate Neuroscience Training to Medical Professionals

    SBC: C4 Innovations, LLC            Topic: 102

    PROJECT SUMMARYABSTRACTWhile biological models of mental illness once emphasizedchemical imbalancesmodern perspectives increasingly incorporate a more nuanced understanding of genetics and epigeneticsneurotransmitters and neuroplasticityand the functional dynamics of neural circuitsYet despite extraordinary advances in neuroscience that have dramatically enhanced our understanding of the brain and ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Phase IIB: Exploratory Clinical trials for The V Needle

    SBC: HEMOTEK            Topic: 400

    HemodialysisHDis generally perceived as a safebenignprocedureBut if venous needle dislodgementVNDoccurs during dialysis and the machine fails to detect itwithin minutes the blood loss can be catastrophicand even fatalIt is estimated thatdialysis patients suffer a dislodgement episode every week in the USIn a Phase I Phase II SBIR partnership with our clinical and medical device partnersHemotek Med ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Development of an oxygen delivery biotherapeutic for the preservation of myocardial function during pediatric cardiopulmonary bypass

    SBC: Omniox, Inc            Topic: NICHD

    PROJECT SUMMARY ABSTRACT Omniox is developing a unique oxygen delivery proteinOMXas a treatment to preserve myocardial and peripheral organ function and significantly reduce morbidity after neonatal cardiopulmonary bypassCPBduring surgical correction of congenital heart diseaseCHDOf thechildren born annually with CHDrequire urgent surgery to repair heart defectsUp toof infants who undergo CPB will ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Supportive Clinical Trial Tasks for Nanotechnology-Based Treatment of Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: NCI

    Preceding AwardNCI AwardRCAProject SummaryAccording to the Oral Cancer Foundationaboutpeople in the US will be newly diagnosed with oral cancerOCincausingdeathsOC is a severely neglected orphan disease with a lack of significant treatment advances indecadesHistoricallyOC has been present in heavy smokers and drinkersHowevermore recently OC has also become more prevalent in younger people due to an ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Motor Unit Drive (MU Drive) for Prosthetic Control

    SBC: ALTEC Inc            Topic: NICHD

    The proposed Phase II SBIR project will develop a unique motor unitMUbased control systemMU Drivethat uses neural firings measured noninvasively and in real time to drive an upper limb prosthesisOur Phase I effort successfully proved the technical merit and feasibility by demonstrating that MU firings can be measured from surface myoelectric recordings in real time and used to provide a proportion ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Array Imaging digital PCR Platform

    SBC: Combinati Incorporated            Topic: 100

    Abstract Combinati is looking to bring an integrated Array Imaging digital PCR platform with injection molded microfluidic consumables from lab to marketplace to accelerate the adoption of dPCR technologyDigital PCR has drawn attentions in both genomic research and clinical research communities for its ability to detect rare eventshigh sensitivityless prone to inhibitionhigh specificityno need for ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Immuno-Oncology for Pancreatic Cancer: A Combination Clinical Trial with Chemotherapy and Radiation

    SBC: ADVANTAGENE, INC            Topic: 102

    DESCRIPTIONprovided by applicantPancreatic adenocarcinoma has a dismalyear survival of andltThe only potential curative treatment is resectionbut this is achieved in andltof patients and most still die due to micrometastases or residual diseasePatients with unresectable disease receive palliative chemotherapy with a median survival of less thanmonthsThis application proposes a multi pronged approa ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. Modulation of the Innate Immune Response by Fisetin Derivatives for the Treatment of AD

    SBC: VIROGENICS, INC.            Topic: NIAID

    AbstractThere are currently no drugs or other therapeutic interventions that can reverse or halt the progression of Alzheimerandapos s diseaseADAge is by far the greatest risk factor for ADand it is known from studies in both mice and humans that neuroinflammation is increased with old age and to an even greater extent in ADThereforea drug that could reduce neuroinflammation and at the same time b ...

    SBIR Phase II 2018 Department of Health and Human Services

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