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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Serum Hepcidin Immunoassay: Laboratory to Marketplace

    SBC: INTRINSIC LIFESCIENCES LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Disorders of iron metabolism are among the most common human diseases. During the last decade, rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders. The peptide hormonehepcidin has emerged as the master regulator of iron metabolism. Dysregulation of hepcidin is the principal or contributing factor in most syste ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. Serum Hepcidin Immunoassay: Laboratory to Marketplace

    SBC: INTRINSIC LIFESCIENCES LLC            Topic: 300

    DESCRIPTION provided by applicant Disorders of iron metabolism are among the most common human diseases During the last decade rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders The peptide hormone hepcidin has emerged as the master regulator of iron metabolism Dysregulation of hepcidin is the principal or contributing factor in most syst ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid point of care test for Lyme serodiagnosis based on novel ultra sensitive de

    SBC: IMMUNETICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Lyme disease is the most prevalent vector borne disease in the U S with about cases per year reported by CDC and a range now covering states Early diagnosis and treatment of Lyme disease is important to prevent the disease from progressing to a systemic infection characterized by chronic arthritis carditis or neurological disorders Where a patien ...

    SBIR Phase II 2014 Department of Health and Human Services
  4. Rapid, disposable, nucleic acid diagnostic device for multiplexed point of care f

    SBC: MESA TECH INTERNATIONAL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Rapid and accurate identification of highly infectious and pathogenic disease is extremely important for the early forecast of outbreak risk and the effective deployment of medical and administrative countermeasures Unfortunately current diagnostics for use at the point of care POC are largely immunological assays that often lack adequate sensitivity speci ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. An Immunoprotectant for Marburg Virus

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: R

    DESCRIPTION provided by applicant Mortality rates associated with Marburg virus MARV outbreaks range from to over MARV is included by the Centers for Disease Control and Prevention as among the Category A agents or andquot high priority agents that pose a risk to national security andquot MARV not only causes acute and terrifying disease but it is relatively stable in wet or ...

    SBIR Phase II 2014 Department of Health and Human Services
  6. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Globally, an estimated 16.2% of the human population is infected with HSV-2 including gt17% of the U.S. adult population. Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV-2infection can cause neonatal herpes with high infant mortality. HSV-2 infection in the adult population has increased substantially in the past ...

    SBIR Phase II 2014 Department of Health and Human Services
  7. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: R

    DESCRIPTION provided by applicant Globally an estimated of the human population is infected with HSV including andgt of the U S adult population Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV infection can cause neonatal herpes with high infant mortality HSV infection in the adult population has increased substantially in the ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. Humanized Antibody Therapeutic to Improve Cardiac Function Following Myocardial I

    SBC: DECIMMUNE THERAPEUTICS, INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary/Abstract Acute myocardial infarction (AMI) affects over 1 million US individuals a year and at the present there are no preventive therapeutics other than direct percutaneous coronary intervention. DecImmune's long-term goal is to develop therapeutics to reduce the severe lethal reperfusion injury that follows removal of coronary artery blo ...

    SBIR Phase II 2014 Department of Health and Human Services
  9. SBIR TOPIC 096:Novel Biodegradable Stents for Neonatal Aortic Coarctation

    SBC: 480 Biomedical Inc.            Topic: NHLBI

    Aortic coarctation is a common congenital heart condition that is usually recognized during the neonatal period early after birth The usual treatment is open surgery Non surgical catheter based stent therapy is not available to treat neonatal aortic coarctation because children outgrow commercially available metallic stents Absorbable stents might revolutionize the treatment of aortic coarctation ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Multiplexed Bead-based In Vitro Pediatric Allergy Test

    SBC: AMBERGEN, INC            Topic: NIAID

    DESCRIPTION provided by applicant This proposal focuses on the development of a high throughput high sensitivity low blood volume multiplex assay for in vitro diagnosis of allergies termed AllerBead tm Allergies comprise a group of immune disorders constituting the th leading cause of chronic disease in the US In the case of pediatric allergies over million children ar affected a nu ...

    SBIR Phase II 2014 Department of Health and Human Services

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