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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Improving Human Performance through Neuroenhancement

    SBC: REJUVENATE BIO INC            Topic: SOCOM182002

    Special Operations Forces (SOF) are an integral aspect of the US military. SOF operators are among the most elite and highly qualified individuals in the U.S. military. As such, extraordinary physical and mental demands are placed upon them to excel in extreme environments for extended periods of time. This unrelenting cycle of combat deployments and intense pre-deployment training shortens the fu ...

    SBIR Phase I 2018 Department of DefenseSpecial Operations Command
  2. Development of Innovative Broad-Spectrum Analysis Methods for PFAS

    SBC: SEACOAST SCIENCE, INC.            Topic: 17NCER3A

    This SBIR addresses EPA’s need for improved sampling and analysis technologies to detect Per- and Polyfluoroalkyl Substances (PFAS). PFAS are used in firefighting sprays, at airports, and for wild fires, and have been used in textile treatments (e.g., it is a component in Scotchgard). It is estimated that 65 million Americans are at risk of PFAS exposure in their drinking water. Seacoast propose ...

    SBIR Phase I 2018 Environmental Protection Agency
  3. Renewable Bioplastics Production

    SBC: Altex Technologies Corporation            Topic: 17NCER5A

    Altex’s Renewable Bioplastics Production (RBP) technology meets the Greener Plastic Manufacturing needs; to eliminate harmful-petrochemical feed sources, to accomplish toxic-free, low-energy, low cost bioplastics production, to reduce Green House Gas (GHG) emissions, and to have environment friendly-biodegradable bioplastics. Altex’s proposed RBP technology combines a novel feeding-sizing-pret ...

    SBIR Phase I 2018 Environmental Protection Agency
  4. Greener Plastics with High Heat Tolerance for Additive Manufacturing

    SBC: Intelligent Optical Systems, Inc.            Topic: 17NCER5B

    Advances in materials and automation are rapidly reshaping the American manufacturing economy. These advances must be embraced to sustain a strong manufacturing sector in the United States. Additive manufacturing is possibly the fastest growing example of this trend, growing at an astonishing compound annual growth rate of 25.7%. The plastic materials market for additive manufacturing, valued at $ ...

    SBIR Phase I 2018 Environmental Protection Agency
  5. Real-time monitoring of inorganic chloramines near swimming pools

    SBC: SEACOAST SCIENCE, INC.            Topic: NCEZID

    Chlorination of swimming pools is necessary to insure swimmers healthhoweverthis process results in the formation of organic and inorganic chloraminesThe presence of volatile inorganic chloramines proximate to the water surface cause a variety of maladiesieirritation to the eyesskinand respiratory systemThe concentration of the chloramines tend to accumulate specifically in indoor poolsIn response ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Prehospital and Emergency Room Stroke Diagnosis Using Quantitative Cerebral Hemodynamics

    SBC: Neural Analytics, Inc.            Topic: NINDS

    Large vessel acute ischemic strokeAISis the leading cause of disability and fourth leading cause of death with approximatelyper year in the United States aloneAlthough treatments including interventionalstentrieverand pharmaceuticaltPAexist for large vessel occlusionLVOthere is not a rapid prehospital tool for diagnoses which guides the use of the correct therapyBecause the time to treatment for s ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions

    SBC: SPIRE, INC.            Topic: NIDA

    PROJECT SUMMARY Recovery from substance use disordersSUDsis greatly impacted by the cognitive and emotional state of the individualand learning new thought and behavioral patterns can facilitate successful treatment and recoverySpecificallyfluctuations in stress or anxiety can trigger lapses to drug useEven when actual use is avoidedstress induced craving is likely to be distracting and to reduce ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. A Novel Therapeutic that Harnesses MIcrotubules to Enhance Corneal Wound Healing Following an Alkaline Burn

    SBC: MicroCures Inc.            Topic: NEI

    The cornea is one of the most important tissues in the eye and its transparency is critical for good visual function in humansCorneal tissue injuries are the most common everyday issue for practicing ophthalmologists and can run the gamut in severityIn severe modelssuch as corneal alkaline burnsextensive healing is needed and often the burn victim is left with reduced visual acuityHealing of large ...

    STTR Phase I 2018 Department of Health and Human Services
  9. A Novel, Low-Cost Device to Guide Peripherally Inserted Central Catheter (PICC) Line Placement

    SBC: Theranova LLC            Topic: NIA

    Abstract Improper placement of peripherally inserted central cathetersPICCsis costly and has serious complications for critically ill patientsMore than one million PICCs are placed each year to provide IV therapieswhere navigation through the venous system is typically performed blindor without navigation guidanceAs a resultof PICC tips are not optimally placed on the first attempt and require rep ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. First-in-human study of MW151, a novel drug targeting neuroinflammation

    SBC: ImmunoChem Therapeutics, LLC            Topic: NIA

    ABSTRACT Alzheimerandapos s diseaseADis one of the largest global public health crises facing us todayyet there are no effective therapies available to preventdelayor slow AD progressionDominant approaches based on a set of prevailing core hypotheses about druggable pathways and targets have failedThereforethere is a need for novel and alternative pathways distinct from those pursued over the past ...

    SBIR Phase I 2018 Department of Health and Human Services

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