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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Long-acting PTH for hypoparathyroidism

    SBC: EXTEND BIOSCIENCES INC            Topic: NIDDK

    Project Summary Hypoparathyroidism is a rare disease that results from a deficiency or inability to make sufficient amounts of parathyroid hormonePTHUntreated or inadequately treated hypoparathyroidism leads to clinically significant mineral related metabolic issues including hypocalcemiawhich leads to heart arrhythmiasspasms of the vocal cordsand seizuresCurrent management of the disease for the ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Development of PAR2 Pepducins as a Novel NASH Treatment

    SBC: OASIS PHARMACEUTICALS, LLC            Topic: 300

    Non alcoholic steatohepatitisNASHis characterized by fatty changes in the liver with inflammation and hepatocellular injury that in advanced stages leads to fibrosiscirrhosis and high mortality ratesNASH is frequently associated with other common metabolic abnormalitiessuch as insulin resistance and visceral obesityLiver transplantation is currently the only effective therapeutic approach for seve ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Commercializing Praedicare Dx TM platform for guiding cancer treatments

    SBC: Eutropics Pharmaceuticals, Inc.            Topic: 102

    Abstract The Eutropics PraediCare Dxis an emerging clinical diagnostic assay that will be used to predict patient response to specific chemotherapiesUnlike existing assaysPraediCare Dxpredicts response to specific chemotherapies by direct evaluation of cancer cells potential to enter into an apoptotic state following exposure to therapyPraediCare Dxhas the potential to provide actionable data for ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. PANDAA for rapid genotyping of HIV-1 infected patients failing protease inhibitor ART in resource-limited settings

    SBC: ALDATU BIOSCIENCES INC            Topic: R

    TheWHO guidelines recommend anti retroviral therapyARTfor all HIV infected peopleand massive efforts to expand ART access will result in andgtM adults and andgtM children on ART byat a cost of almost US$BConsequentlythe number of patients prescribed alternativeprotease inhibitorPIbased ART following failure of first line regimens will also increaseStudies of patients on PI based ART in resource li ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Eliminating Ventricular Tachycardia:First in Human Clinical Trial using the Durablate Catheter

    SBC: Thermedical Inc.            Topic: NHLBI

    Ischemic ventricular tachycardiaVTcauses more than half of thesudden cardiac deathsSCDthat occur annually in the United StatesImplantable cardioverter defibrillatorsICDsare the standard of carebut they are expensivethe total cost of an ICD implant exceeds $and not curativePatients who receive ICDs are subject to periodic shocks to halt episodes of VTand those shocks can be traumaticRF ablation rep ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Albumin Nanoparticles Incorporating Piceatannol (PANPs) for ALI/ARDS therapy

    SBC: NANO BIOTHERAPEUTICS INC            Topic: NHLBI

    Sepsis induced ALI ARDS is a devastating syndrome of acute respiratory failure in critically ill patients that accounts for among the highest admission rates in ICU and mortalityDuring STTR Phasewe at Cell Biologics Incdemonstrated that piceatannola naturally occurring anti inflammatory that selectively inhibits Syk tyrosine kinasewhen entrapped in innm albumin nanoparticlesPANPswas therapeuticall ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease

    SBC: BIOSENSICS LLC            Topic: 106

    ABSTRACT The principal means of measuring motor impairment in Huntington diseaseHDis the Unified Huntington s Disease Rating ScaleUHDRStotal motor scorewhich is subjective and categoricalWearable sensors could enable objectivesensitivecontinuous assessment of motor impairments in individuals with a variety of neurological movement disordersThis is important because large amounts of objective data ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Service-based Command and Control (C2) for the Forward Deployed Energy and Communications Outpost (C2-FDECO)

    SBC: CHARLES RIVER ANALYTICS, INC.            Topic: N091082

    Advances in the capabilities of the US Navy’s fleet of unmanned underwater vehicles (UUVs) have led to an array of assets capable of executing a number of operational missions. The Navy is investing in extending the reach of these assets to provide mission capabilities from longer range and over longer duration. The FDECO Innovative Naval Prototype (INP) program addresses one challenge of curren ...

    SBIR Phase II 2017 Department of DefenseNavy
  9. Long-acting ghrelin for the treatment of cancer cachexia

    SBC: EXTEND BIOSCIENCES INC            Topic: 102

    Project Summary Cachexia is a complex syndrome characterized by involuntary weight loss and skeletal muscle wasting that leads to fatigueweakness and a loss of appetite that is not reversed by increased caloric consumptionMore than half of all cancer patients develop cachexia and it is responsible for more thanof all cancer deathsNumerous complications associated with cachexia include an impaired ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Adapting the Berkeley Big Data Analytics Stack to Genomics and Health

    SBC: CURII CORP            Topic: 400

    Project Summary We propose building a computational platform based on the high performance Berkeley Big Data Analytics StackBDASto support a new ecosystem of Clinical Decision SupportCDSapplicationsThis platform will make it fastereasierand less expensive to develop molecular Clinical Decision Support SystemsThese systems require real time queries of globally distributed dataefficient machine lear ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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