Award Data

DESCRIPTION provided by applicant Diffuse large B cell lymphoma DLBCL represents one of the most common variants of Non Hodgkinandapos s lymphoma NHL and oncogenic herpesviruses EBV and KSHV are the etiologic agents for the majority of these tumors in patients over or those infected with the human immunodeficiency virus HIV Despite modest improvements in outcomes for patients rece ...

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

DESCRIPTION provided by applicant Amyotrophic lateral sclerosis ALS or Lou Gehrigandapos s disease is a fatal neurodegenerative disease with a typical lifespan of years after diagnosis The initial symptoms can be similar to many other neurologic disorders and often begin with limb weakness muscle fasciculations or increasing difficulties in speech or breathing No definitive diagnost ...

DESCRIPTION provided by applicant Lipella Pharmaceuticals Inc Pittsburgh PA is a clinical stage pharmaceutical company specializing in intravesical therapies for urinary bladder dysfunctions Lipella is submitting a research proposal to the Small Business Technology Transfer program titled andquot Developing Intravesical Liposomes for Interstitial Cystitisandquot The project proposes to e ...

DESCRIPTION provided by applicant The goal of this STTR Phase II collaboration between Purdue University and bioVidria Inc is to commercialize disruptive new technology for protein chromatography and then maximize its impact by serving the fastest growing segment of the pharmaceutical industry protein drugs The product is a reversed phase chromatography column that uses silica particles of ...

This project address the fabrication of solar blind detectors from the MgZnO material system. Both MBE and MOCVD material growth techniques will be used for deposition of the required material layers. Simulation software we be used to aid in the design of the photodetector structure. Devices will be fabricated from the grown structures and their electrical and optical characteristics determined.

We propose a wearable, dual-use neurotechnology device. The Personal Brainwave Headband, driven by tablet or smartphone, is designed for noninvasive closed-loop acoustic stimulation, to permit improved circadian regulation. It will measure brain electrical activity from scalp overlying four key sectors of cortex, perform high-resolution spectral analysis of the signals, and use software algorith ...

Few-cycle mid-infrared lasers are highly demanded for a variety of practical applications. NP Photonics and University of Arizona propose to develop a wavelength tunable and power-scalable optical parametric laser system at 8-12 micron capable of producing collimated few-cycle pulses with pulse energy>100 microJoule. In this phase I program, we will design the whole laser system and do a feasibil ...

We propose a rapid mapping and 3-D visualization system especially suited for inside buildings, tunnels, urban canyons, and other environments where GPS may be poor or not available. The system--which was fully demonstrated in our Phase I effort-- includes mobile Sensor Nodes that wirelessly supply compressed 3D range data and color imagery to a central Fusion Node. The Fusion Node runs 3D recon ...

DESCRIPTION (provided by applicant): About 3-4% of all fractures are estimated to be open fractures, where the fracture is exposed through defects in the skin and soft tissues. This equates to about 250,000 open fractures in the United States annually. Open fractures present a high risk of infection. Infection results in considerable financial burden to both the patient an healthcare system, requ ...