You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A vaccine against Clostridium difficile infections

    SBC: SORRENTO THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): In this proposal we lay out a comprehensive research plan to evaluate our vaccination strategies targeting Clostridium difficile to prevent or treat infections. With the emergence of highly antibiotic-resistant bacterial strains, new approaches for combating bacterial infections are desperately needed. In this research proposal, Sorrento Therapeutics Inc. (STI ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Liposomal Nicotine Vaccine Development

    SBC: MOLECULAR EXPRESS, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): In response to RFA-DA-11-004, we propose in this STTR Phase I application to develop and test a nicotine vaccine utilizing a chemical derivative of the drug, or hapten, coupled to an immunostimulatory, adjuvant-containing liposome. The current approach to curbing nicotine addiction is the use of over the counter nicotine replacement products, but this approach ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. In vivo and in vitro tools to target CHRNA5 for smoking cessation.

    SBC: OPHIDION, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Nicotine is one of the most heavily used addictive drugs and accounts for 90% of lung cancer cases in the U.S. Recent studies have implicated a specialized receptor class binding to nicotine, the CHRNA5 gene, which encodes the a5 subunit of the nicotinic receptor, as a contributing factor in the risk towards nicotine dependence. This, along with animal studies ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Bi-frequency PC-MUT Co-linear Array for Ophthalmic Imaging

    SBC: Blatek, Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): Ultrasound imaging of the anterior segment, posterior segment and the full lens contour is important in diagnosis of glaucoma, cataracts, etc. eye disease, eye surgery guidance and post surgery assessment. High resolution, large field of depth and rapid electronic scanning are necessary to obtain accurate images of eye as a whole. Blatek, NCSU and USC team ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Injury-targeted decorin for systemic anti-fibrotic treatment

    SBC: VASCULAR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The repair of injuries is dominated by a tendency to re-establish tissue continuity rather than restoring the structure of the original tissue. This process results in scarring and fibrosis, which is a major medical problem spanning diseases in all organ systems. This application focuses on a compound that has been shown to be highly effective in reducing scarr ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. An Acoustic Respiratory Movement Sensor (ARMS) to Produce and Monitor SIMV in Inf

    SBC: BIODATA INNOVATION SYSTEMS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): This project will demonstrate the feasibility of the use of non-contacting acoustic respiratory movement sensor (ARMS) for a device that will be used as a sensor for a module that can trigger any commercially availableneonatal ventilator to produce non-invasive synchronized ventilation. Synchronization of the ventilator improves gas exchange, decreases the leng ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. PF4 antagonists as therapeutics for heparin induced thrombocytopenia and thrombos

    SBC: IN SILICO MOLECULAR, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The ultimate aim of this project is to produce a drug for the prevention and treatment of heparin induced thrombocytopenia and thrombosis (HITT), a serious complication of heparin therapy for which there is currently nospecific treatment. Heparin is a naturally-occurring anticoagulant that prevents the formation of clots and extension of existing clots within t ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Medicinal Chemicals: Cardiomyogenesis from Human Stem Cells

    SBC: ChemRegen Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 1-2% of Americans greater than 65 years of age have heart disease. According to the American Heart Association, heart failure is one of the most common causes of hospitalization for patients over 65 years of age inthe Western world and as the population ages, this situation will only get worse. Currently, more than 5 million Americans suffer from heart fai ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Small Molecule Toolbox: Cardiomyocytes from Human Stem Cells

    SBC: ChemRegen Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): It is estimated that more than 5 million Americans suffer from heart failure. The economic cost to US society for heart disease was almost 40 billion per in the year 2009. Currently, people with late-stage heart failure have only two treatment options, a heart transplant or implantation of a mechanically-assisted heart device but in the US, just over 2,000 hea ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Screening New Therapeutics for the Treatment of Post Traumatic Stress Disorder

    SBC: Azevan Pharmaceuticals Inc            Topic: NIMH

    DESCRIPTION (provided by applicant): Project Summary/Abstract Post-traumatic Stress Disorder (PTSD) is recognized by the NIMH, the Department of Defense, and the Veterans' Administration as a major medical issue. Recent studies indicate that the incidence of PTSD among Iraq and Afghanistan veterans is 20% and may reach 35%, a rate far higher than in the general population. PTSD is not on ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government