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Many blood simulants that are currently available for medical training to teach and practice hemorrhage-handling skills lack the ability approximate real blood in many aspects. In order to provide the best training, the blood simulant needs to mimic the

There is a substantial clinical need for regenerative therapies that effectively restore function to damaged tissues. For many tissues, autograft remains the clinical standard despite the limited volume available, associated patient morbidity and the resu

Head and neck surgeons are often challenged by the paucity of autografts to reconstruct large CMF defects; a grafting technology for replacing and regenerating lost tissue is needed. To address this OSD need, Physical Optics Corporation (POC) proposes to

Regenerative cell therapy using adult mesenchymal stem cells (MSCs) offers great potential to therapeutic cartilage repair. However, the current MSC chondrogenesis method of using TGF-beta is inefficient and assumes fibrocartilage-like features and hyper

An automated, closed loop system for administration of analgesic and anesthetic medication to patients is proposed. Even with vigilant, trained personnel, infusion rates of propofol and other analgesic/anesthetic drugs can depart from their optimum rates,

Sterling Point Research has assembled an interdisciplinary team composed of researchers from Children"s Hospital Boston and Boston University, an anesthesiologist, and a former U.S. Army medic to develop a Deployable Remotely Enabled Analgesia Management

Minimally invasive surgery (MIS), including laparoscopic surgery (LS), is beneficial in terms of the improved recovery of the patient, including shorter convalescence times, less postoperative pain, and less scarring. Training surgeons in these new techni

The field of surgical simulation is fairly crowded with many products and research groups developing physical and virtual simulators. Much of this previous work is in simulating minimally invasive surgeries. The considerable body of work generated in de

This proposal is to develop an integrated Collaborative Information Infrastructure for Planning, Operations and Evaluation (CIIPOE). The CIIPOE will include capabilities for critical information integration, COA development and evaluation, operations pla

To address the OSD need for web-based, Sharable Content Object Reference Model (SCORM)-compliant, photorealistic, virtual medical training tools in a serious medical game, Physical Optics Corporation (POC) proposes to develop a new Serious Medical Online/