Award Data

A principal approach in regenerative medicine is to stimulate or augment endogenous repair mechanisms that promote functional restoration of damaged or diseased tissues. When loss of significant volumes of multiple functionally integrated tissues occurs,

Head and neck surgeons are often challenged by the paucity of autografts to reconstruct large CMF defects; a grafting technology for replacing and regenerating lost tissue is needed. To address this OSD need, Physical Optics Corporation (POC) proposes to

Regenerative cell therapy using adult mesenchymal stem cells (MSCs) offers great potential to therapeutic cartilage repair. However, the current MSC chondrogenesis method of using TGF-beta is inefficient and assumes fibrocartilage-like features and hyper

The control of pain, anxiety, discomfort, and the sequellae of injury and illness is an over-arching healthcare issue in both military and civilian settings. Current strategies for pain relief, sedation and anesthesia involve infusion of intravenous agen

This proposal is to develop an integrated Collaborative Information Infrastructure for Planning, Operations and Evaluation (CIIPOE). The CIIPOE will include capabilities for critical information integration, COA development and evaluation, operations pla

To address the OSD need for web-based, Sharable Content Object Reference Model (SCORM)-compliant, photorealistic, virtual medical training tools in a serious medical game, Physical Optics Corporation (POC) proposes to develop a new Serious Medical Online/

To address the Office of Secretary of Defense"s need for a synthetic tissue trainer, Physical Optics Corporation proposes to develop a Synthetic Human Medical (SY-MAN) Trainer to limit live animal use. The SY-MAN trainer is based on a combination of multi

We propose to develop a family of stand-alone synthetic tissue/organ training systems to replace live animal tissue and cadaver training for the Air Force Medical Modeling & Simulation Program, as well as for other surgery training facilities. The develop

Farus, LLC proposes to develop a novel burn assessment tool based upon THz imaging that will be aid in determining severity and boundaries. THz is ideally suited to burn wound imaging because it is extremely sensitive to water, robust to scattering, non-ionizing, and does not require contrast agents. A complete THz imaging system developed by a UCLA research team successfully scanned skin burns o ...

We propose to develop a swift, non-contact imaging-based solution to objectively assess variable depths of injury in burned soldiers while suggesting appropriate standardized treatment plans. Currently, determination of burn depth and healing outcomes has been limited to subjective assessment or a single modality, e.g., laser Doppler imaging. Such measures have proven less than ideal. Recent devel ...