Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development and Demonstration of Virus-Inspired DNA Origami (VIDO) Vaccines

    SBC: PARABON NANOLABS, INC.            Topic: OSD11H01

    Parabon NanoLabs (PNL) has designed and demonstrated the feasibility for a new hybrid vaccine nanostructure that is based upon a DNA origami that can include protein antigens or epitopes, immune stimulators, cell targeting ligands and a transfection plasmid.This approach offers the opportunity for crafting molecularly defined vaccine nanostructures that stimulate a specific primary response that i ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  2. Tissue Engineered Vascular Graft

    SBC: TECHSHOT, INC.            Topic: DHP14009

    Techshot is pleased to provide this phase II proposal to continue our exciting scaffold development work in creating a Tissue Engineered Vascular Graft (TEVG).This off the shelf conduit will be capable of being combined with the patients own cells either at the time of surgery or by healing and remodeling in situ to provide a long term solution to revascularization due to traumatic injury.We inten ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  3. Objective Measurement Tool for Detection and Monitoring of Noise-Induced Hearing Loss

    SBC: Mimosa Acoustics Inc.            Topic: DHP15015

    We propose to take our binaural OtoStat-HCP hearing-test system, which was designed for advanced hearing-conservation programs (HCPs), and ruggedize it for use in theater. OtoStat-HCP includes pure-tone audiometry, otoacoustic emission (OAE), and wideband immittance tests. Commercial-off-the-shelfOAE systems are unsuitable for HCPs, so we will: 1) implement next-generation OAE tests to enable qual ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  4. Lateral Canthotmy and Cantholysis Training System

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHP15001

    The lateral canthotomy and cantholysis (LCC) procedure is required for pre-deployment training at the US Army Center for Pre-Hospital training at Fort Sam Houston as mandated in executive order HQDA 096-09. This order cannot be fully executed, however, since a realistic, hands-on LCC skill development module does not exist prior to animal training. Although the technique is potentially vision-savi ...

    SBIR Phase I 2016 Department of DefenseDefense Health Program
  5. Combinatorial Nanofiber-Based Analgesic Dressings for Burn Wounds

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: A14048

    Current thermal and chemical burn care practices such as debridement and physical therapy produce intense pain for patients. The management of this intense pain relies almost exclusively on systemically administered opioids or other pain medications, which are known to produce side effects as serious as opioid dependence.The need to reduce opioid use can be met by delivering the known effective op ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  6. Technologies for Treating Cartilage Tissue Loss Following Traumatic Injury

    SBC: Spheringenics, Inc.            Topic: OSD10H04

    Regeneration of cartilage and cartilage repair are challenging due to limited cellularity of the tissue and the failure of allografts and tissue engineered cartilage constructs to integrate with host tissue. To overcome this limitation, many surgeons are

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  7. A Nano-pharmaceutical Platform for Creating Artificial Vaccines

    SBC: PARABON NANOLABS, INC.            Topic: OSD11H01

    In this project, Parabon NanoLabs (PNL) will demonstrate the feasibility of extending its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce Essemblix-V, a platform for creating artificial vaccines from a predefined set of"building block molecules"assembled on DNA origami. Given an epitope for a potential ...

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  8. Non-Radiological Imaging Devices for Combat Casualty Care Associated with Burn

    SBC: SED Technology LLC            Topic: OSD11H03

    SED Technology LLC is proposing an existing concept of determining burn area and depth based on extensive previous work involving infrared technology. The proposed concept involves the use of all capabilities associated with 2D and 3D Infrared that have been developed by Dr. Francine Prokoski in the areas of Biometrics, Forensics and Health Care applications. The concept could eventually provide a ...

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  9. Cultural Logic Understanding Engine (CLUE)

    SBC: DECISIVE ANALYTICS CORPORATION            Topic: OSD10HS1

    Without some way to acquire or access insight into the social dynamics of battlespace populations, Warfighters will operate with a limited or inaccurate understanding of the human terrain and an impeded ability to explain current social behavior and to pr

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  10. Neuromonitoring of Traumatic Brain/blast Injury

    SBC: EMPIRICAL TECHNOLOGIES CORPORATION            Topic: OSD09H06

    The objective of the proposed program is the development of a mobile and non-invasive cerebro-physiological monitor that will permit the tracking of cerebral functions and the identification of developing pathologic brain conditions in wounded soldiers during transport and under medical care in forward areas. Specifically, the purpose of the system will be to continuously track cerebral blood flow ...

    SBIR Phase II 2011 Department of DefenseDefense Health Program
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