Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Rapid Response Vaccines for Botulinum Neurotoxins

    SBC: Iterative Therapeutics Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most potent protein toxins known. Given their potent toxicity and their potential use in bio-warfare scenarios, BoNTs are included among the Category A select agents. The currentlyavailable pentavalent toxoid vaccine requires multiple boosters before being effective, and protects unequally against the different BoNT serotyp ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. Multifunctional Peptides for (MRI) Imaging

    SBC: CDG THERAPEUTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Our overall goal is to expand the role of CPPs in molecular imaging at the patient level using large animal models of human tumors and a peptide agent that inherently provides 1) preferential access to a wide variety ofhuman solid (and hematologic) tumor cells, 2) an increased intracellular concentration (2-12 fold) over histologically matched normal cells, and ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. Optimal Prevention and Control of Periodontal Disease: The Periodontal Pocket Irr

    SBC: C. PAXTON DESIGNS INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Periodontal disease is a chronic bacterial infection that affects the gums and bone that surrounds supported teeth. According to the NIH fact sheet an estimated 80 percent of American adults have some form of periodontal disease. Gingivitis, a milder form of gum disease, is caused by plaque bio-film, which surrounds the teeth at the base of the gum line, causin ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. New drug Vida-5 for treating chronic kidney disease progression

    SBC: Vidasym, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Anemia, cardiovascular diseases, secondary hyperparathyroidism, renal osteodystrophy and other complications are common in CKD. Current treatmentsincluding ACE inhibitors for CKD patients mainly focus on managing symptoms and disease complications. Despite the various treatments available, ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. E-Learning Assisted HAZWOPER Training for Coroners and Medical Examiners

    SBC: D&E TECHNICAL, INC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Human death investigations must by law be properly implemented even when the decedent is involved in or near to the scene of a hazardous materials emergency. This project intends to develop worker health and safety training for those staff of coroners and medical examiners who investigate deaths in hazardous materials environments. This innovative training will ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Portable Instrument for Chemifluorescent Detection of Lead in Dust

    SBC: Strategic Government Business Consulting Group, Ltd            Topic: NIEHS

    DESCRIPTION (provided by applicant): Lead poisoning has been identified as the number one environmental health problem in the United States affecting children. The CDC estimates that 30 percent of in inner city children have high lead levels and that one million children have lead levels greater than 10 5g/dL of blood. Childhood exposure to low levels of lead have been shown to cause permanent neu ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Testing Feasibility of SlipChip Workflow for Membrane Protein Crystallization

    SBC: SLIPCHIP, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Membrane proteins are crucial to a wide variety of physiological processes, functioning as chemical receptors, transport channels and signal transducers. It is estimated that over half of drug targets are membrane proteins. Structural knowledge of membrane proteins is of very high biomedical significance. Crystallization of membrane proteins is an important app ...

    SBIR Phase I 2011 Department of Health and Human Services
  8. SlipChip for Target Enrichment for Next-Gen Sequencing by Multiplexed PCR

    SBC: SLIPCHIP, LLC            Topic: NHGRI

    DESCRIPTION (provided by applicant): 1. For the past 30 years, Sanger sequencing has enabled the determination of a sequence of nucleotide 2 bases on a small segment of DNA, with the crowning achievement of the technology being the complete 3 elucidationof the human genome at a cost of several hundreds of millions of dollars. Recently, next- 4 generation sequencing technologies have been deve ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. NIH SBIR Phase I: UNCD as Bio-Inert Interface for Anti-Thrombogenicity Applicati

    SBC: Advanced Diamond TechNologies, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Due to the gruesome toll of cardiovascular disease (CVD) through-out the world, improvements in treatment for CVD are of profound medical, societal and economic importance. The proposed research will be conducted in collaboration with renowned artificial heart pioneer, Dr. Robert Jarvik, and is designed to improve the operating lifetime of Ventricular Assist De ...

    SBIR Phase I 2011 Department of Health and Human Services
  10. NIH SBIR Phase I: Development of a Novel Boron-doped Ultrananocrystalline Diamond

    SBC: Advanced Diamond TechNologies, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): There is an enormous need for the development of a new class of chemical microsensors that are versatile, selective, sensitive and reliable to allow investigation of the neurobiological mechanisms of behavior and disease symptoms. Currently, the preferred method for monitoring neurotransmitters in vivo real time is fast- scan cyclic voltammetry (FSCV) and the p ...

    SBIR Phase I 2011 Department of Health and Human Services
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