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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Rapid Response Vaccines for Botulinum Neurotoxins
SBC: Iterative Therapeutics Inc. Topic: NIAIDDESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most potent protein toxins known. Given their potent toxicity and their potential use in bio-warfare scenarios, BoNTs are included among the Category A select agents. The currentlyavailable pentavalent toxoid vaccine requires multiple boosters before being effective, and protects unequally against the different BoNT serotyp ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Multifunctional Peptides for (MRI) Imaging
SBC: CDG THERAPEUTICS, INC. Topic: NCIDESCRIPTION (provided by applicant): Our overall goal is to expand the role of CPPs in molecular imaging at the patient level using large animal models of human tumors and a peptide agent that inherently provides 1) preferential access to a wide variety ofhuman solid (and hematologic) tumor cells, 2) an increased intracellular concentration (2-12 fold) over histologically matched normal cells, and ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Multi-day Pain Management Therapy with Novel Injectable Formulation
SBC: ORBIS BIOSCIENCES, INC. Topic: NIDADESCRIPTION (provided by applicant): Our long term goal is to widespread the use of PPF technology for promoting effective production of drug-encapsulating microparticles with uniform size and physical characteristics that can be leveraged to release a specific drug at controlled rates over multi-day periods in vivo after a single administration. For this proposal, we are specifically targeting a ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Optimal Prevention and Control of Periodontal Disease: The Periodontal Pocket Irr
SBC: C. PAXTON DESIGNS INC. Topic: NIDCRDESCRIPTION (provided by applicant): Periodontal disease is a chronic bacterial infection that affects the gums and bone that surrounds supported teeth. According to the NIH fact sheet an estimated 80 percent of American adults have some form of periodontal disease. Gingivitis, a milder form of gum disease, is caused by plaque bio-film, which surrounds the teeth at the base of the gum line, causin ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Anti-CD47 mAb Therapy to Improve Kidney Transplantation
SBC: VASCULOX, INC. Topic: NIDDKDESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. While there have been manyrecent strides in organ procurement, preservation and follow-up immune suppression, prevention of ischemia-reperfusion injury (IRI) remains prob ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
New drug Vida-5 for treating chronic kidney disease progression
SBC: Vidasym, Inc Topic: NIDDKDESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Anemia, cardiovascular diseases, secondary hyperparathyroidism, renal osteodystrophy and other complications are common in CKD. Current treatmentsincluding ACE inhibitors for CKD patients mainly focus on managing symptoms and disease complications. Despite the various treatments available, ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
E-Learning Assisted HAZWOPER Training for Coroners and Medical Examiners
SBC: D&E TECHNICAL, INC Topic: NIEHSDESCRIPTION (provided by applicant): Human death investigations must by law be properly implemented even when the decedent is involved in or near to the scene of a hazardous materials emergency. This project intends to develop worker health and safety training for those staff of coroners and medical examiners who investigate deaths in hazardous materials environments. This innovative training will ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Portable Instrument for Chemifluorescent Detection of Lead in Dust
SBC: Strategic Government Business Consulting Group, Ltd Topic: NIEHSDESCRIPTION (provided by applicant): Lead poisoning has been identified as the number one environmental health problem in the United States affecting children. The CDC estimates that 30 percent of in inner city children have high lead levels and that one million children have lead levels greater than 10 5g/dL of blood. Childhood exposure to low levels of lead have been shown to cause permanent neu ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Nanocomposite Imaging System for the Eye
SBC: KYPHA INC. Topic: NEIDESCRIPTION (provided by applicant): The purpose of this SBIR project is to develop a new dual-modality inflammation imaging technology to early detect Uveitis, an ocular inflammation-related disorder. This technology, based on nanocomposites (NCs) that function as dual-modality fluorescent and acoustic contrast agents for optical and ultrasound imaging techniques, will allow both quantitative ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Testing Feasibility of SlipChip Workflow for Membrane Protein Crystallization
SBC: TALIS BIOMEDICAL CORP Topic: NIGMSDESCRIPTION (provided by applicant): Membrane proteins are crucial to a wide variety of physiological processes, functioning as chemical receptors, transport channels and signal transducers. It is estimated that over half of drug targets are membrane proteins. Structural knowledge of membrane proteins is of very high biomedical significance. Crystallization of membrane proteins is an important app ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health