Award Data

Recent research has shown that Superconducting Quantum Interference Devices (SQUIDs) may be used to measure the very weak magnetic signals in Magnetic Resonance Imaging (MRI) at ultra-low magnetic fields in the milli-tesla range or below. However, the signal-to-noise ratio (SNR) is quite low, requiring very long averaging times to obtain reasonable spatial resolution. Under the Phase I project, we ...

This Phase I project is relevant to the ultimate goals of this program announcement given the prevalence of the IED which often creates complex burn wounds on the face and skin that often form hypertrophic scars that often contract over time. Burn wound healing is a complex process that includes phases of inflammation, granulation tissue formation, re-epithelialization, and, finally, remodeling. ...

Military medical personnel are not prepared to provide trauma care to severely injured soldiers in wartime due to inadequate and unrealistic battlefield training opportunities during peacetime. Training has historically been done on human cadavers and live animals, but cadavers are in limited supply, and animal rights groups and physicians are increasing pressure to end the practice of using live ...

Multiple studies have identified physiological and behavioral variables that are associated with pain intensity in critical care patients. In this phase of the research, we propose to investigate the feasibility of developing a multi-modality pain intensity detection algorithm predicated on physiological and behavioral indicators of pain as well as designing a plan to"calibrate"and validate the pa ...

The goal of this project is to implement a Universal Exchange Language suitable for nationwide adoption across healthcare providers, and accessible to patients and medical researchers under appropriate protections for security and privacy, as envisioned in the 2010 PCAST report on Health Information Technology. The team combines unique expertise on (a) the design and implementation of data managem ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

The majority of personnel injured in OIF/OEF have suffered blast injuries from IEDs. Blasts often cause cranio-facial trauma that is difficult to repair surgically. The current standard of care involves the placement of fixation devices and off label use of growth factor carriers. These strategies often require multiple surgical interventions creating a significant need for better technologies ...

Current toxicity testing of foodstuffs involves mass spectrometry analysis which requires a>24 h turnaround time in deployed military operations. This length of time is dangerous for personnel. Rapid identification of toxic industrial chemicals (TICs) in food using a sensor that is biologically-based and easy to use eliminates that danger and would provide exactly what is needed for toxicity eva ...

The control of pain, anxiety, discomfort, and the sequellae of injury and illness is an over-arching healthcare issue in both military and civilian settings. Current strategies for pain relief, sedation and anesthesia involve infusion of intravenous agen

A principal approach in regenerative medicine is to stimulate or augment endogenous repair mechanisms that promote functional restoration of damaged or diseased tissues. When loss of significant volumes of multiple functionally integrated tissues occurs,