Award Data

In this project, Parabon NanoLabs (PNL) will demonstrate the feasibility of extending its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce Essemblix-V, a platform for creating artificial vaccines from a predefined set of"building block molecules"assembled on DNA origami. Given an epitope for a potential ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

SED Technology LLC is proposing an existing concept of determining burn area and depth based on extensive previous work involving infrared technology. The proposed concept involves the use of all capabilities associated with 2D and 3D Infrared that have been developed by Dr. Francine Prokoski in the areas of Biometrics, Forensics and Health Care applications. The concept could eventually provide a ...

The objective of the proposed program is the development of a mobile and non-invasive cerebro-physiological monitor that will permit the tracking of cerebral functions and the identification of developing pathologic brain conditions in wounded soldiers during transport and under medical care in forward areas. Specifically, the purpose of the system will be to continuously track cerebral blood flow ...

Operational Technologies Corporation (OpTech) has completed a successful Phase I SBIR contract in which 72 new candidate DNA aptamer sequences against Leishmania major were developed and screened by ELISA-like plate assay. Several pilot assays were developed from the highest affinity candidate aptamers using a commercially available handheld and battery-operated fluorometer. In Phase II, OpTech p ...

The problem of inaccurate patient identification due to errors introduced during data capture or due to syntactic and semantic differences between patient registration systems is one of the biggest challenges facing healthcare today. An inefficient and inaccurate master patient index introduces duplicate and/or overlaid patient records which can then cause inappropriate or delayed treatments, adve ...

Current toxicity testing of foodstuffs involves mass spectrometry analysis which requires a>24 h turnaround time in deployed military operations. This length of time is dangerous for personnel. Rapid identification of toxic industrial chemicals (TICs) in food using a sensor that is biologically-based and easy to use eliminates that danger and would provide exactly what is needed for toxicity eva ...

MedWorld will apply virtual world gaming techniques to enable military medical personnel to experience the impact of real world conditions in performance of their duties, whether they are on the battlefield or in a stateside hospital. MedWorld is struc

Regeneration of cartilage and cartilage repair are challenging due to limited cellularity of the tissue and the failure of allografts and tissue engineered cartilage constructs to integrate with host tissue. To overcome this limitation, many surgeons are

The control of pain, anxiety, discomfort, and the sequellae of injury and illness is an over-arching healthcare issue in both military and civilian settings. Current strategies for pain relief, sedation and anesthesia involve infusion of intravenous agen