Award Data

Recent research has shown that Superconducting Quantum Interference Devices (SQUIDs) may be used to measure the very weak magnetic signals in Magnetic Resonance Imaging (MRI) at ultra-low magnetic fields in the milli-tesla range or below. However, the signal-to-noise ratio (SNR) is quite low, requiring very long averaging times to obtain reasonable spatial resolution. Under the Phase I project, we ...

Microfabricated chemical and biological sensors serve as an interface between biologic and electronic systems. Previously, through TATRC-funded research grants (W81XWH-05-2-0064, W81XWH-10-1-0358), we have investigated the behavior and detection of propofol using electrochemical (EC) methods. Using these analytical methods, we have quantified the oxidation of propofol well below therapeutic concen ...

Military medical personnel are not prepared to provide trauma care to severely injured soldiers in wartime due to inadequate and unrealistic battlefield training opportunities during peacetime. Training has historically been done on human cadavers and live animals, but cadavers are in limited supply, and animal rights groups and physicians are increasing pressure to end the practice of using live ...

Multiple studies have identified physiological and behavioral variables that are associated with pain intensity in critical care patients. In this phase of the research, we propose to investigate the feasibility of developing a multi-modality pain intensity detection algorithm predicated on physiological and behavioral indicators of pain as well as designing a plan to"calibrate"and validate the pa ...

The goal of this project is to implement a Universal Exchange Language suitable for nationwide adoption across healthcare providers, and accessible to patients and medical researchers under appropriate protections for security and privacy, as envisioned in the 2010 PCAST report on Health Information Technology. The team combines unique expertise on (a) the design and implementation of data managem ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

Applications for ultrasound are expanding beyond medical imaging to include new functionality, with the potential to halt internal bleeding or provide an alternative to manual suturing. These types of functions are suited to a surgical robot, offering the potential for tele-operation or even autonomous functionality. However, the requirements for positioning an ultrasound device are different th ...

Current toxicity testing of foodstuffs involves mass spectrometry analysis which requires a>24 h turnaround time in deployed military operations. This length of time is dangerous for personnel. Rapid identification of toxic industrial chemicals (TICs) in food using a sensor that is biologically-based and easy to use eliminates that danger and would provide exactly what is needed for toxicity eva ...

The control of pain, anxiety, discomfort, and the sequellae of injury and illness is an over-arching healthcare issue in both military and civilian settings. Current strategies for pain relief, sedation and anesthesia involve infusion of intravenous agen