Award Data

Skeletal muscle injury is a significant challenge to warfighters due to the severity of the injuries often caused by Improvised Explosive Devices. Currently, there are few viable clinical treatment options for these types of injuries. Keratin hydrogels offer a solution to these challenges as carriers of cells and growth factors. Human epithelial keratins are the major structural proteins in cel ...

Injuries to soft tissues in extremities represent a high percentage of battlefield wounds in recent conflicts. Therapies for restoring function to injured muscle are needed for Wounded Warriors suffering from debilitating and sometimes disfiguring musculoskeletal injuries. Regenerative medicine holds promises of new treatment strategies, yet there remains significant need to develop better platfo ...

This project will bring interferometric synthetic aperture microscopy (ISAM), a powerful new method of computed microscopy, to bear on the problem of quantitative tissue assessment. The promise of tissue engineering, including wound healing, is limited unless the tissue is treated correctly at optimal times during growth. Therefore, continuous, nondestructive, microscopic 3-D visualization and qu ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

The majority of personnel injured in OIF/OEF have suffered blast injuries from IEDs. Blasts often cause cranio-facial trauma that is difficult to repair surgically. The current standard of care involves the placement of fixation devices and off label use of growth factor carriers. These strategies often require multiple surgical interventions creating a significant need for better technologies ...

Chemical imaging sensors require focal plane arrays (FPAs) incorporating long wavelength infrared (LWIR) detectors suitable for hyperspectral detection. These detectors require high sensitivity to account for the low photon counts in narrow wavelength bands. The required sensitivity elevates the associated costs, so a need exists for a lower cost LWIR FPA for use with chemical imaging sensors. The ...

A principal approach in regenerative medicine is to stimulate or augment endogenous repair mechanisms that promote functional restoration of damaged or diseased tissues. When loss of significant volumes of multiple functionally integrated tissues occurs,

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this proposal is to demonstrate the feasibility of building a data management system for DN ...

In the wake of the September 11th attacks and subsequent Anthrax scares, researchers worldwide are working to expand our ability to rapidly assess what poses a terrorism threat to the public. The rapid detection of specific pathogens is required for biod

Ventilation systems are extremely venerable to incidental and malicious attacks by terrorists and saboteurs. During attacks by chemical and biological weapons, personnel in temporary and permanent shelters are dependent on a constant supply of clean air. Consequently, the main objective of the proposed work is to develop a microwave low-temperature catalytic oxidation system that will effectively ...