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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder

    SBC: LOHOCLA RESEARCH CORPORATION            Topic: 150

    Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Graspable Math Activities

    SBC: GRASPABLE INC            Topic: 91990018R0006

    Through previous grant awards from IES, researchers developed Graspable Math, a tablet-based intervention where middle and high school students create and manipulate complex expressions for basic operations as well as equations and equations systems and inequalities. In this project, the team will develop a prototype of Graspable Math Activities, an app with novel kinds of algebra practice and ass ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  4. Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)

    SBC: Imago Systems, Inc.            Topic: NCI

    Immunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy. In this Contract, Imago Systems, Inc., a company with substantial experience i ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A system to detect fall occurrence and location in hospital settings

    SBC: BARRON ASSOCIATES, INC.            Topic: NIA

    Fall detectionassessmentand prevention is a challenging issue across the care continuumDespite wide recognition as a considerable problemfall related injuries are still the most frequently reported adverse events in hospital inpatient settingswithof patients falling at least once during their stayAccording to the Agency for Healthcare Research and Quality reportstoof falls result in injuryIn the U ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Nonsense Suppressing Drugs for Rett Syndrome

    SBC: Starwise Therapeutics LLC            Topic: 103

    Nonsense Suppressing Drugs for Rett Syndrome Rett syndromeRTTis a devastating genetic condition that affects mostly femalesIt is one of the worst types of neurodevelopmental disordersthe affected girls are born without any obvious problemsdevelop in a seemingly typical manner for the first year of lifebut then abruptly and without warning lose most of their acquired abilitiesRTT girls then typical ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. BT-11: A First-in-class Oral Therapeutic for Inflammatory Bowel Disease

    SBC: Biotherapeutics, Inc.            Topic: NIAID

    BTA First in class Oral Therapeutic for Inflammatory Bowel Disease Biotherapeutics IncBTIdevelops oral first in class therapeutics for autoimmune diseasesBTa lead compound for treating inflammatory bowel diseaseIBDbelongs to a new chemotype and targets the novel Lanthionine Synthetase C LikeLANCLpathwayBTI will file an IND for BTinmonthsSignificanceIBD afflicts overmillion Americans andmillion peo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Powerful Solid-State Sources to Enable Advanced EPR and DNP-NMR Measurements

    SBC: VIRGINIA DIODES, INC.            Topic: 400

    VDI Project Summary AbstractThe NIH Division of Cell Biology and Biophysics supports studies of the biological macromolecules that affect the function and structure of living cellsand often play a role in diseaseWithin the realm of biophysicsone of the most important tools to study the structure and interactions of these molecules is nuclear magnetic resonanceNMRFor exampleNMR has been used to stu ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Integrated System for Rapid Production of Activated Sugars and Glycosylated Molecules

    SBC: ZUCHEM INC.            Topic: 300

    Glycan modifications of natural products are increasingly important in the discovery of new pharmaceuticalsWhile glycodiversity gives rise to important therapeutic properties of bioactive moleculesexploring glycodiversity has challengesIsolating glycosylated compounds from nature is often difficult due to low concentrations and the presence of multiple related molecules with similar structures and ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Middle-ear reflex testing using WAI

    SBC: Mimosa Acoustics Inc.            Topic: NIDCD

    PROJECT SUMMARYThe purpose of the proposed project is to combine wideband acoustic immittanceWAIand middle ear muscle reflexMEMRtesting using new approaches that improve sensitivityincrease test efficiencyand provide objectivity in interpretationAcoustically elicited MEMRs have a long history of value in the clinical evaluation of hearing lossWhile sensitive to and affected by middle ear disorders ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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