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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Creating a predictive vascular system for early development

    SBC: HemoShear Therapeutics, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The frequent inability of in vitro assays and animal models to accurately predict human response to a new drug candidate results in costly drug development failures. HemoShear has developed a platform technology for biodiscovery and drug pharmacology screening that replicates human biological function in healthy and diseased organ systems by applying human-deri ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Development of next-generation Thrombelastographs

    SBC: CORAMED TECHNOLOGIES            Topic: NHLBI

    DESCRIPTION (provided by applicant): Coramed is commercializing next-generation point of care instruments, the TEG 6000 series, for monitoring patient hemostasis on demand. This project includes activities to take the technology from the prototype stage completed in Phase II to FDA-cleared and CLIA-waived commercial products. The planned devices introduce a completely new technology for monitoring ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This application, “Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein- protein interaction,” addresses the critical need for more effective medications to treat chronic neuropathic pain affecting ~116 million people in the United States. Current pain medications such as NSAIDS, steroids, opiates and gabapentin analogs have documented and often severe sid ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Clinical Evaluation of a New Middle Ear Diagnostic to Support FDA Regulatory Clearance

    SBC: PhotoniCare, Inc.            Topic: NIDCD

    PROJECT SUMMARY IntroductionPhotoniCareIncis a medical device company nearing commercializing the ClearViewa handheldoptical imaging device for improved diagnosis of middle ear healthThe purpose of this proposaldeveloped in conjunction with the affiliated FDA review committeeis to perform pivotal clinical studies and use the collected data to establish objective data analysis algorithms for FDAkcl ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Real-time volumetric specimen imager for 3D intra-operative lumpectomy margin assessment

    SBC: Clarix Imaging Corporation            Topic: 102

    Project Summary We propose to develop a novel volumetric specimen imagerVSIsystem for significantly reducing breast lumpectomy s reoperation rate and improving cosmetic outcomesAmong the annual performance of andgtlumpectomies in the USaboutof patients need reoperationswhen post surgery pathology examination revealspositive marginindicating incomplete tumor removal in initial surgeryCurrently phys ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Small Molecule Inhibitors of PCSK9-Phase II

    SBC: Hingez Therapeutics Inc            Topic: NHLBI

    Abstract Heart disease remains the leading cause of death in the USaccounting for nearlyof all deaths annuallyA high cholesterol level is a well known risk factor for heart diseaseAlthough blood cholesterollow density lipoproteinLDL Ccan be lowered using a number of marketed drugsonlyof patients taking these drugs are achieving the desired goalsFurthermorepatients with homozygous familial hypercho ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Integrating CNV analysis into a NextGen sequencing clinical analytics platform

    SBC: Golden Helix, Inc.            Topic: 400

    Abstract The goal of this project is to develop a commercial analysis software platform that features the ability to detect and interpret copy number variantsCNVsand other types of structural variationsSVsfrom short read NextGen SequenceNGSdata to enable comprehensivewidely accessibleand economical genetic testingThis capability is key in clinical and research applicationsFor examplecurrently clin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Targeted Polymerized Shell Microbubbles to Image and Treat Surgical Adhesions

    SBC: NanoValent Pharmaceuticals, Inc.            Topic: 300

    Project Summary The long term goal of this Phase II SBIR project is to develop a commercially viable ultrasound contrast reagentUCRthat will allow the noninvasive identification and treatment of newly forming abdominal adhesions after surgerySuccessful implementation would have significant impact because we would both improve patient post surgical monitoring and considerably reduce the cost of adh ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a diagnostic instrument to manage hemostasis in chronic liver dise

    SBC: HEMOSONICS            Topic: NIDDK

    DESCRIPTION (provided by applicant): The clinical evaluation and management of hemostasis in the 5 million patients affected by chronic liver diseases (CLD) is poorly understood. Data presented at two International Symposia on Coagulation in Liver Diseaseand summarized in a recent edition of Clinics in Liver Disease strongly support the presence of an unmet clinical need for investigation in this ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  10. NeuroScience Practical Applications to Reach K-12 Students (NeuroSPARKS)

    SBC: BARRON ASSOCIATES, INC.            Topic: 500

    PROJECT SUMMARY ABSTRACT SignificanceNeuroSPARKS is a unique learning system that leads students through lesson modules to introduce STEM concepts in an imaginative and engaging platformThe system combines inexpensivewireless electromyography electrodes that are convenient for students to use in a classroom setting with software that presents STEM lessons within a video gameThe NeuroSPARKS project ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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