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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: MOLECULAR TARGETING TECHNOLOGIES, INC.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Graspable Math Activities

    SBC: GRASPABLE INC            Topic: 91990018R0006

    Through previous grant awards from IES, researchers developed Graspable Math, a tablet-based intervention where middle and high school students create and manipulate complex expressions for basic operations as well as equations and equations systems and inequalities. In this project, the team will develop a prototype of Graspable Math Activities, an app with novel kinds of algebra practice and ass ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  4. History Maker

    SBC: Schell Games LLC            Topic: 91990018R0006

    In this project, the team will develop a prototype of History Maker, a virtual reality (VR) content creation tool, where students and teachers produce digital movies to be used as reports and/or presentations about particular historical topics. Within the platform, students will research primary sources documents, write scripts, and act scenes from history. Student work will be presented in VR to ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  5. Thermostable Savin IPV

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: ODCDC

    PoliomyelitisPoliois a highly infectious disease that primarily affects young childrenCurrentlythe live attenuated oral poliomyelitis vaccineOPVis the vaccine used to prevent polio outbreaks and stop transmission of wild poliovirusesHoweversometimes OPV has the ability to revert to a form that can cause paralysis or poliomyelitiswhich will inevitably lead to new polio outbreaksIn most developed co ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. Finding Human Carriers of Taeniasis to Prevent Neurocysticercois Associated Epilepsy

    SBC: APTAGEN LLC            Topic: ODCDC

    NeurocycsticercosisNCCis a leading cause of adult onset epilepsy in the developing world and an increasing public health concern in the United StatesNCC develops in individuals infected with tape worm Taenia soliumTsoliumHowevermost people are unaware of their infection before neurological symptoms appearthus posing a major risk of transmitting the infectionReliable diagnosis and efficacious treat ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. Self Stable Corneal Tissue Storage Solutions with Antifungal Additives

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: ODCDC

    There has been a recent rise in the rate of fungal infections following corneal transplant surgeries over the last six yearsand most cases have been tied to donor to recipient transmissionWhile preliminary studies have demonstrated the efficacy and safety of adding antifungal agents to the corneal storage media to minimize the risk of infectionthe shelf life of these antifungal agents is significa ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)

    SBC: Imago Systems, Inc.            Topic: NCI

    Immunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy. In this Contract, Imago Systems, Inc., a company with substantial experience i ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 373: Monoclonal Antibodies to RNA-modifications

    SBC: ABZYME THERAPEUTICS LLC            Topic: NCI

    Post-transcriptional RNA modification is quite complex as there are more than sixty known RNA modifications that occur in thousands of RNAs in eukaryotic cells. A number of these RNA modifications have been shown to influence the development and physiology of the central nervous system (CNS) and to be involved in carcinogenesis. Despite the growing interest in and importance of RNA modifications, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 373: Novel Mass Spectrometry Methods and Research Tools to Map Nucleotide Modifications in Cytosolic Transfer RNAs from Cancer Cells

    SBC: Ribonova Inc.            Topic: NCI

    Chemical modifications play a crucial role in the regulation of biological processes. Protein function is often modulated by tagging with phosphates, sugars, or lipids, while epigenomic marks on DNA or histones can regulate gene expression up or down. One area that lags behind is the mechanistic understanding of the role of RNA chemical modifications, sometimes referred to as the 'epitranscriptome ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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