Award Data

Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

Ample evidence exists that US military operational information is released via social media and internet sources; possibly compromising operational security (OPSEC). IST Research designed, in Phase I, Managing Operations Security Tool (MOST) to detect and characterize these OPSEC threats in online data and propose mitigation techniques. MOST supports identity management and force protection profes ...

The balance between the advantages and liabilities of sharing personal and organizational digital information continues to be tested. While modern information technologies have provided tremendous boosts to personal, corporate and public-sector capability growth, they also expose a vulnerability that can cripple organizations and put personal livelihoods at great risk. For U.S. Government person ...

New high performance materials, seamed with novel bonding methods, combined with advanced aerodynamic designs, will be employed to develop lighter, more compact parachutes and paragliders, with improved aerodynamic performance and stability.

Rigid wall shelter protection against electromagnetic threats has historically been provided by passive steel or aluminum skins on the shelter walls. However, these legacy shelters require high levels of maintenance and corrosion protection; do not meet current International Standards Organization (ISO) and Convention of Safe Container (CSC) standards for stack height; are not energy efficient and ...

This project will modify GFE (delivered under contract N68335-15-C-0102, to be returned to Fibertek), test the modified system, and deliver an advanced blue solid-state laser transmitter based on frequency doubling of a diode pumped near infrared laser. The technical approach utilizes a novel gain module design which maximizes pump efficiency while minimizing temperature rise and thermally induced ...

Ferrium M54 is an ultrahigh-strength, high, toughness steel with high resistance to grinding burn damage, and stress corrosion cracking, which provides many technical and commercial benefits for use in the F-18 E/F/G hook point application over the incumbent 4330V steel. The technical advantages for risk mitigation, while extending the component life at approximately the same cost makes for a good ...

The primary objective of this SBIR initiative is to develop, demonstrate, and validate new manufacturing technologies. The focus is complex parts made from refractory metals manufactured at reduced costs and increased fabrication rates. The target components are for use in post-boost control system (PBCS) hot-gas valves and manifolds. Emphasis on and addressing scale up for fabrication of full-sca ...

The focus of this Phase II SBIR topic is to develop an extremely small SWaP ISR/EW capability. There is a need and associated requirements within the Navy and other Department of Defense (DOD) agencies to detect, geo-locate, and discriminate emitters of interest in littoral and open ocean environments. Larger intelligence data demand and fewer manned intelligence platforms make it difficult to mee ...