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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Fast and Accurate Tools for Measuring Fluorescence in Living Cells

    SBC: MONTANA MOLECULAR LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): Project Summary/Abstract Drug discovery depends crucially upon reliable assays for biological activity. Live cell assays provide a rich environment for measuring biological activity. Coupled with genetically encodedfluorescent biosensors, live cell assays have the potential to provide read-outs with unprecedented specificity for particular signaling pathway ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Tetrahydrocannabinol Prodrugs for Topical Treatment of Glaucoma

    SBC: ElSohly Laboratories, Incorporated            Topic: NEI

    DESCRIPTION (provided by applicant): Currently, FDA approved clinical applications of 9-Tetrahydrocannabinol (THC) include control of nausea and vomiting associated with chemotherapy and for appetite stimulation for AIDS patients suffering from anorexia and wasting syndrome. However, THC also has significant potential in the treatment of glaucoma, the second largest cause of blindness, by dec ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Enhanced Dynamic Range Proteomic Analysis: Phase II

    SBC: RESONON, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The long-term goal of this effort is to develop an optical module that will reduce stray light within imaging systems, thereby providing more accurate measurements from digital images and increased dynamic range of detection to enable analysis of objects not currently measurable. The present Phase II proposal is aimed at greatly enhancing the analysis of multic ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Microwave Technology for Superfund Site Remediation

    SBC: CHA CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of the proposed work is to build a commercial-scale portable microwave system that is capable of regenerating 50-kg/hrof saturated carbon. This process will also be capable of recovering solv

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Anthrax Vaccine Formulations Combining PA/Spore Epitopes

    SBC: LIGOCYTE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Pulmonary anthrax, a rare but extremely severe form of anthrax, is initiated by phagocytosis of Bacillus anthracis spores by alveolar macrophages (AMs). The current, Protective Antigen (PA) based, vaccine requires sev

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Antifungal Denture Adhesive Film for Oral Candidiasis

    SBC: MIKKUR, INC.            Topic: N/A

    DESCRIPTION: The overall goal of this project is to investigate the feasibility of a novel technology to produce an "Antifungal Denture Adhesive Film" (ADA) System that will minimize or eliminate the current shortcomings of oral mucosal treatment modaliti

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a High Performance Bioreactor

    SBC: RESODYN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The Phase II project specific aim is to perform research to develop and demonstrate an advanced, High Performance Bioreactor (HPBR) fermentation technology that enhances growth characteristics and product expression f

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Hypoxia-Perfusion Bioreactor for Stem Cell Applications

    SBC: RESODYN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Cord blood (CB) cells are a desirable source of stem cells for transplantation because their collection poses no donor impact and they would facilitate the creation of an ethnically diverse pool of donor cells. However

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Mechanical Induced Resonant Mixing for Islet Separation

    SBC: RESODYN CORPORATION            Topic: N/A

    The proposed research is aimed to develop a mechanically-induced resonant mixing process for pancreas islet cell separation. The proposed study incorporates a unique mixing technology into a Resonant Enhanced Enzyme Tissue Digester (REETD) design. The REE

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Acoustically-Enhanced Myogenic Cell Culture

    SBC: RESODYN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The use of human muscle cells for tissue engineering applications holds significant promise for new treatments of muscle-cell disorders, organ repair, and gene therapy. With the enabling advances in biology and immun

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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