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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. DBM Anti-Proliferative Lead Small Molecules for Polycystic Kidney Disease

    SBC: DISCOVERYBIOMED, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): An important discovery and validation event occurred recently within human cell-based drug discovery programs at DiscoveryBioMed, Inc. (DBM), yielding a lead class of cytostatic anti-proliferative small molecules thatdisplay nanomolar potency and marked efficacy against hyperproliferative human PKD cells that create and line remodeled PKD cysts within emergent ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Laboratree: A Web-based Research Collaboration System

    SBC: SELICAN TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): Solutions for enabling collaboration continue to be a challenge for biomedical informatics service providers. With the recent rise of so-called Science 2.0 web based tools, many solutions have been proposed using Internet technology including wiki's, document management systems, and custom websites. Here we propose utilizing an open platform, Google's OpenSocia ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Identification and Validation of Targets of Phenotypic High Throughput Screening

    SBC: Prosolia, Inc.            Topic: NIGMS

    DESCRIPTION: Development of an Intelligent Sample Introduction System for Mass Spectrometry There is a pressing need for new technologies that enable rapid measurements without significant compromise to the analytical data. Herein, we propose to develop arobust mass spectrometry (MS) based surface sampling device that enables direct analysis of a variety of materials including biological tissue a ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Cystic Fibrosis Corrector Ligands Discovered in CF Human Airway Cells

    SBC: DISCOVERYBIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposed Phase I SBIR program, DiscoveryBioMed, Inc. (DBM) will continue to build upon an active project performed in collaboration with CFTR cell biologists at the University of Alabama at Birmingham and alternative rescue chloride (Cl-) channel physiologists at Johns Hopkins University School of Medicine. DBM developed a novel and simple SPQ halide-se ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR TOPIC321:CHEMICALLY DEFINED GLYCAN LIBRARIES FOR REFERENCE STANDARDS AND GLY

    SBC: OMICRON BIOCHEMICALS, INC.            Topic: NCI

    Cell-surface oligosaccharides appended to proteins and lipids are key binding epitopes in many critical biological processes, including bacterial infection, cell development and the immune response. Understanding these processes at the molecular level requires access to a wide range of oligosaccharides of known structure to support investigations of enzyme substrate binding and specificity, to ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Novel VLP Adjuvant based on the VesiVax system

    SBC: Euclid Diagnostics LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Over one million prostate biopsies are performed in the US each year to diagnose approximately 200,000 cases of prostate cancer. The majority of these biopsies are performed needlessly. The overall objective of this project is to develop a secondary prostate cancer diagnostic test that can be performed on men with elevated PSA in order to identify patients in n ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR TOPIC 314: DEVELOPMENT OF A HUMAN TISSUE CULTURE SYSTEM THAT MIMICS THE TUMO

    SBC: Vivo Biosciences Inc            Topic: NCI

    Not Available

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Portable device for monitoring water balance in elderly

    SBC: 3dt Holdings, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Transseptal (TS) access for left heart procedures is an important and rapidly growing space for diagnostics and therapy delivery with an expected total of over 10 million U.S. patients. In the U.S. and/or Europe, TS access procedures are used for atrial fibrillation (AF) ablation, left atrial appendage (LAA) closure, patent foramen ovale (PFO) closure, and trea ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. System for Increasing Patient Access to Eye Exams for Diabetic Retinopathy

    SBC: AEON IMAGING, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. NIEHS- Device Agnostic Environmental/Agent Data Collection and Integration with

    SBC: APEX Therapeuitcs, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Our long-term goal is to develop a novel therapeutic strategy for childhood acute lymphoblastic leukemia (ALL), with focus on relapsed T-cell leukemia. We intend to accomplish this by targeting a unique molecular masterregulator using a new generation of compounds. ALL is the most frequent cancer of the childhood. Although significant progress has been achieved ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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