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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Novel VLP Adjuvant based on the VesiVax system

    SBC: Euclid Diagnostics LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Over one million prostate biopsies are performed in the US each year to diagnose approximately 200,000 cases of prostate cancer. The majority of these biopsies are performed needlessly. The overall objective of this project is to develop a secondary prostate cancer diagnostic test that can be performed on men with elevated PSA in order to identify patients in n ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. NIEHS- Device Agnostic Environmental/Agent Data Collection and Integration with

    SBC: APEX Therapeuitcs, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Our long-term goal is to develop a novel therapeutic strategy for childhood acute lymphoblastic leukemia (ALL), with focus on relapsed T-cell leukemia. We intend to accomplish this by targeting a unique molecular masterregulator using a new generation of compounds. ALL is the most frequent cancer of the childhood. Although significant progress has been achieved ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Identification and Validation of Targets of Phenotypic High Throughput Screening

    SBC: Prosolia, Inc.            Topic: NIGMS

    DESCRIPTION: Development of an Intelligent Sample Introduction System for Mass Spectrometry There is a pressing need for new technologies that enable rapid measurements without significant compromise to the analytical data. Herein, we propose to develop arobust mass spectrometry (MS) based surface sampling device that enables direct analysis of a variety of materials including biological tissue a ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Multi-Functional Guidewire for Peripheral Vasculature

    SBC: 3dt Holdings, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 8 million Americans have peripheral vascular disease (PAD). Percutaneous transluminal artery (PTA) treatment of severe PAD involves the use of balloons and stents, but delivery of these therapies is often suboptimal due to inaccuracies in angiographic assessment of vessel size or a lack of proper functional vessel assessment. Additional tools aid clinician ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Portable device for monitoring water balance in elderly

    SBC: 3dt Holdings, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Transseptal (TS) access for left heart procedures is an important and rapidly growing space for diagnostics and therapy delivery with an expected total of over 10 million U.S. patients. In the U.S. and/or Europe, TS access procedures are used for atrial fibrillation (AF) ablation, left atrial appendage (LAA) closure, patent foramen ovale (PFO) closure, and trea ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A mechanism-based computational tool to optimize pulmonary drug delivery

    SBC: 3dt Holdings, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Coronary artery disease (CAD) is a national and worldwide epidemic that places the largest clinical and economic burden on the healthcare system of any disease condition. Patients with stable and acute coronary conditions are often treated with percutaneous coronary intervention (PCI), including stenting. Up to 85% of all coronary stents are under-deployed lead ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR TOPIC321:CHEMICALLY DEFINED GLYCAN LIBRARIES FOR REFERENCE STANDARDS AND GLY

    SBC: OMICRON BIOCHEMICALS, INC.            Topic: NCI

    Cell-surface oligosaccharides appended to proteins and lipids are key binding epitopes in many critical biological processes, including bacterial infection, cell development and the immune response. Understanding these processes at the molecular level requires access to a wide range of oligosaccharides of known structure to support investigations of enzyme substrate binding and specificity, to ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. System for Increasing Patient Access to Eye Exams for Diabetic Retinopathy

    SBC: AEON IMAGING, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Elastic biodegradable ureteral stent

    SBC: AKINA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase I study is to develop elastic, biodegradable ureteral stents that will degrade in the body within 2 weeks after a procedure. Current ureteral stents are made of non-degradable polymers and, unless they are permanent, have to be removed by second procedure, which requires further intervention on the patients. Biodegradable ureteral st ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Telephone screening test for hearing using three-digit sequences in noise.

    SBC: COMMUNICATION DISORDERS TECHNOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project will develop a speech-recognition test in noise (SRTn) for use as a screening test for hearing disability, suitable for delivery over the telephone. Successful development and implementation of such a test has the potential to greatly increase awareness of hearing disorders and the numbers of persons with hearing impairment who seek services. The t ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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