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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Cloud based watershed and terrestrial ecosystem data management,integration and analytics

    SBC: SUBSURFACE INSIGHTS            Topic: 01c

    Actionable understanding of watershed and ecosystem behavior is required for a wide spectrum of societal and engineering needs by both government entities and commercial entities- These needs include, for example, water resource management, precision agriculture and hydropower- Such actionable understanding requires the ability to numerically model various coupled processes and associated reaction ...

    SBIR Phase I 2018 Department of Energy
  2. Real time measurement system for coupled surface/subsurface processes

    SBC: SUBSURFACE INSIGHTS            Topic: 22b

    Actionable understanding of watershed and ecosystem behavior is required for a wide spectrum of societal and engineering needs by both government entities and commercial entities- These needs include, for example, water resource management, precision agriculture and hydropower- Such actionable understanding requires the ability to numerically model various coupled processes and associated reaction ...

    SBIR Phase I 2018 Department of Energy
  3. Targeting the checkpoint regulator VISTA for treatment of inflammatory disease

    SBC: IMMUNEXT, INC.            Topic: R

    ImmuNext has identified and developed a putative lead anti VISTA monoclonal antibody mAb that we aim to bring to the clinic for the treatment of human autoimmune disease VISTA is a member of the highly successful negative checkpoint regulator NCR family of drug targets whose members have demonstrated proven efficacy in inducing long term remissions in human cancers We contend that antibodie ...

    SBIR Phase I 2017 Department of Health and Human Services
  4. Bioimpedance based Intracranial Mapping for Monitoring Evolving TBI

    SBC: RYTEK MEDICAL, INC.            Topic: 105

    ABSTRACT Approximately million individuals suffer from traumatic brain injury TBI annually with over expected to die as a result of their injury In these most severe cases patients are typically admitted to the intensive care unit ICU for continuous monitoring and treatment of their injury Standard monitoring includes implantation of an intracranial pressure ICP sensor arterial ...

    STTR Phase I 2017 Department of Health and Human Services
  5. Design and Development of Immunotolerant S aureus Biotherapies

    SBC: Lyticon LLC            Topic: NIAID

    The increasing incidence of multi drug resistance in Staphylococcus aureus and other bacteria represents a public health crisis Two thirds of hospital associated S aureus infections and of those acquired in the community are now methicillin resistant MRSA MRSA causes andgt infections in the US each year and it is responsible for half of all US deaths caused by drug resistant bac ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Preclinical development of inhalable glutaredoxin for the treatment of IPF

    SBC: CELDARA MEDICAL, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Idiopathic pulmonary fibrosis IPF kills about persons in the United States each year There are currently around Americans afflicted with this fatal disease that typically results in death within years This year alone another approximately Americans will receive this devastating diagnosis While two recently approved drugs reduce the ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Development of GIFT a B cell focused immunotherapy for cancer

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    Project Summary Our goal is to develop a novel immunotherapy for the treatment of melanoma and potentially a wide array of tumors Although surveillance by the immune system eliminates cancer cells in some instances tumor cells have developed a variety of mechanisms to escape immune recognition often resulting in tumor outgrowth Immune checkpoint inhibitors e g ipilimumab nivolumab and pemb ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Real-Time In-Situ Measurement of Void Fraction and Specific Surface in Fresh Concrete

    SBC: CREARE LLC            Topic: 171FH2

    Water expansion during freeze-thaw cycles can cause deterioration in concrete, leading to scaling, cracking, and crumbling over a period of years. Resistance to this damage is achieved with a system of voids formed by adding surfactants to the fresh concrete to stabilize air bubbles naturally entrained during mixing. The volume fraction, size, and spacing of these voids are critical. It is importa ...

    SBIR Phase I 2017 Department of Transportation
  9. RailMonitor: Real-Time Broken Rail Detection System

    SBC: CREARE LLC            Topic: 171FR2

    Broken rails are a common cause of mainline derailments and a particular concern given the increasing use of our rail system for passenger traffic and petroleum products. The progressive nature of the defects provides an opportunity for early detection of cracks before they become significant enough to cause a derailment. Unfortunately, current inspection technology does not allow these inspection ...

    SBIR Phase I 2017 Department of Transportation
  10. Improved Thermal and Acoustic Comfort for Motorcycle Helmets

    SBC: CREARE LLC            Topic: 151NH1

    Use of motorcycles helmets significantly reduces the risk of fatality or serious brain injury to riders in the event of a crash, but riders often do not wear helmets in warm weather because of thermal discomfort. We propose to develop an innovative ventilation and cooling system that will maintain a cool, dry environment inside the helmet while also meeting applicable safety standards. The key the ...

    SBIR Phase II 2017 Department of Transportation

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