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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Targeting the checkpoint regulator VISTA for treatment of inflammatory disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has identified and developed a putative lead anti VISTA monoclonal antibody mAb that we aim to bring to the clinic for the treatment of human autoimmune disease VISTA is a member of the highly successful negative checkpoint regulator NCR family of drug targets whose members have demonstrated proven efficacy in inducing long term remissions in human cancers We contend that antibodie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Bioimpedance based Intracranial Mapping for Monitoring Evolving TBI

    SBC: RYTEK MEDICAL INC            Topic: 105

    ABSTRACT Approximately million individuals suffer from traumatic brain injury TBI annually with over expected to die as a result of their injury In these most severe cases patients are typically admitted to the intensive care unit ICU for continuous monitoring and treatment of their injury Standard monitoring includes implantation of an intracranial pressure ICP sensor arterial ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Broad Spectrum Electromagnetic Sensing Using Passive and Active Fraction Injection Transient Responses and the Feasibility of Uniquely Separating Fracture and Proppant Distributions

    SBC: Multi Phase Technologies LLC            Topic: 18b

    Tracking both the extent of the induced fracture and the distribution of the proppant within the fracture are critical in understanding and optimizing the hydraulic fracture processes. Several groups are studying the use of electromagnetic methods and electrically conductive proppants to image the post-fracture proppant distribution. Interpreting these large-scale electromagnetic surveys will like ...

    SBIR Phase I 2017 Department of Energy
  4. Real-Time In-Situ Measurement of Void Fraction and Specific Surface in Fresh Concrete

    SBC: CREARE LLC            Topic: 171FH2

    Water expansion during freeze-thaw cycles can cause deterioration in concrete, leading to scaling, cracking, and crumbling over a period of years. Resistance to this damage is achieved with a system of voids formed by adding surfactants to the fresh concrete to stabilize air bubbles naturally entrained during mixing. The volume fraction, size, and spacing of these voids are critical. It is importa ...

    SBIR Phase I 2017 Department of Transportation
  5. RailMonitor: Real-Time Broken Rail Detection System

    SBC: CREARE LLC            Topic: 171FR2

    Broken rails are a common cause of mainline derailments and a particular concern given the increasing use of our rail system for passenger traffic and petroleum products. The progressive nature of the defects provides an opportunity for early detection of cracks before they become significant enough to cause a derailment. Unfortunately, current inspection technology does not allow these inspection ...

    SBIR Phase I 2017 Department of Transportation
  6. Spouted Fluid Beds for Mercury Removal from Coal

    SBC: MICROBEAM TECHNOLOGIES INCORPORATED            Topic: 18a

    This Small Business Innovation Research project targets the development of mitigation strategies to decrease mercury and other potential hazardous elements in coal prior to combustion or gasification. The Microbeam team including the University of North Dakota and Envergex, LLC is developing a method of coal beneficiation that not only removes mercury, sulfur and other hazardous trace elements, bu ...

    STTR Phase I 2017 Department of Energy
  7. Topic 16a- Low-Cost Desalination System Driven by Hydrokinetic Power

    SBC: CREARE LLC            Topic: 16a

    Ocean and tidal currents contain a huge amount of power that is currently untapped. This power could be used very efficiently to desalinate water for water-poor regions located near coastlines. A major obstacle is the high cost of manufacturing and deployment of ocean systems. We propose an innovative new technology that can dramatically reduce the manufacturing and deployment costs of hydrokineti ...

    SBIR Phase I 2017 Department of Energy
  8. A Field Deployable Electrochemical Sensor to Nondestructively Evaluate De-alloying in Gray Cast Iron

    SBC: MFS Technovation Corp.            Topic: 29e

    Gray cast iron piping is the most common pipe material in North America. Based on the high carbon content, graphitic needles or flakes are a common feature in these alloys. As a result, these areas of super-saturated carbon will consistently establish galvanic attack of the adjacent iron matrix, especially when in the presence of most ionic liquids. The localized galvanic potentials create microsc ...

    STTR Phase I 2017 Department of Energy
  9. Advanced Analysis of Geothermal Heat Pump System Data

    SBC: Ground Energy Support LLC            Topic: 07a

    Geothermal heat pumps utilize heat pump technology to access the ubiquitous and plentiful renewable thermal energy in the shallow subsurface. While there are tremendous potential economic and environmental benefits in the development of this resource, high up‐front installation costs and lack of confidence in the performance of geothermal heat pump systems are significant market barriers to the ...

    STTR Phase I 2017 Department of Energy
  10. Novel Inhibitors of PSMB and PSMB for the Treatment of Multiple Myeloma

    SBC: InhiProt            Topic: 103

    Multiple myeloma is incurable hematologic malignancy with an expected median survival of years The proteasome inhibitors bortezomib carfilzomib and the recently approved ixazomib are a mainstay of current myeloma treatment Despite an initial response rate approaching to proteasome inhibitor containing combinations all patients relapse and eventually become resistant to any treatments ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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