Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. The Variant Explorer: a cloud-based data integration and visualization system for improving clinical interpretation of sequenced genetic variants.

    SBC: Solve, Inc.            Topic: 400

    Project Summary SolveBio is the operating system for molecular informationSolveBio provides data infrastructure with genomics specific mapping technology and application programming interfacesAPIsand graphical user interfacesGUIsfor scientistsbioinformaticiansand software engineersThe goal of this Phase II SBIR proposal is to develop the Variant ExplorerVEa cloud based graphical analysis software ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Splice sensors for cancer drug discovery

    SBC: Lucerna Inc.            Topic: 102

    SUMMARYRNA splicing plays a central role in the generation of proteome diversity and in gene regulationSplicing impacts vital cellular processessuch as cell fate and differentiationacquisition of tissue identityand organ developmentThusdefects in splicing has been linked to many diseasesincluding spinal muscular atrophyDuchenne muscular dystrophyParkinson s diseaseand several types of cancerRNA sp ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Minimally Invasive Cardiac Sympathetic Denervation for Malignant Ventricular Arrhythmia

    SBC: Coridea, LLC            Topic: NHLBI

    Sympathetic innervation of the heart plays a critical role in arrhythmogenesis and recent studies have highlighted the role of surgical sympathetic denervation in management of refractory ventricular arrhythmiasThe procedure although safe is very invasive and performed via thoracoscopy using single lung ventilationThis is not tolerated by patients with lung disease or severe structural heart disea ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. SpliceCore: A Cloud-Based Software Platform to Translate Alternative Splicing Events into Therapeutic Targets Using RNA-seq Data

    SBC: Envisagenics, Inc.            Topic: 400

    Abstract Overmillion people in the US suffer from genetic diseases or cancers caused by mutations of whichdisrupt the regulation of splicingAlternative splicingASerrors have been reported in literature to drivegenetic diseases out ofdescribed to dateIn additiondue to the recent success of FDA approved splicing modulators like Nusinersenalong with fascinating preclinical results underlining the imp ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Expressive Speech Synthesis for Speech-Generating Devices

    SBC: SYNFONICA LLC            Topic: NIDCD

    Project SummaryThe expression of emotions through speech is an essential element of human communicationyet individuals with speech impairments who rely on speech generating devicesSGDsto talk are largely deprived of this communicative channelNo one should be forced to sound blaswhen in fact they re elated or to sound apathetic when they intend to scoldWhile certain expressive speech modes are offe ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. IOBIO based, distributed genomic data access, management, visualization, and analysis

    SBC: Frameshift Labs, Inc.            Topic: 172

    The precision medicine initiative coupled with advances in genomic research and diagnostics isleading to vast increases in the volume of genomic data being createdwith some estimates statingit will outstrip the storage requirements of YouTube byEnsuring all this data can becost effectively managedand that experts from the biomedicalinformatics and medical disciplinescan easily collaborate on analy ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Augmented Reality Sensor Simulation System for HAZMAT Training

    SBC: CELL PODIUM LLC            Topic: 142

    Summary AbstractAugmented Reality HAZMAT Sensor Simulator Phase II A goal of HAZMAT training exercises is to present learners with realistic tasks and experiences involving mock hazardsprotective equipmentPPEtoolsand hazard sensorsHoweverwhile mock hazardsPPEand tools are readily available to trainerssensors that operate with mock hazards are notBecause the decisions that a HAZMAT worker makes are ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimer's Disease

    SBC: PreCyte Inc            Topic: NIA

    Project SummaryPreCyte is developing the Indicator Cell Assay PlatformiCAPas a broadly applicable and inexpensive blood based assay that can be used for the early detection of diseasedisease stage stratificationprognosis and predicting response to therapy for a variety of diseasesThe iCAP uses culturedstandardized cells as biosensorscapitalizing on the ability of cells to respond to disease signal ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. FMRI Dynamic Phantom for Improved Detection of Resting-State Brain Networks

    SBC: ALA SCIENTIFIC INSTRUMENTS, INC.            Topic: R44

    Abstract Functional magnetic resonance imagingfMRIhas rapidly become the dominant tool in human neuroscience researchand is poised to become a transformative technology in the areas of psychiatric and neurological diagnosticsIn recent yearslarge scale$M $B USDand long termyearinternational investmentse gNIDA Adolescent Brain Cognitive Development StudyNIH Human Connectome ProjectWhite House BRAIN ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government