Award Data

In today’s Urban-Warfare Command and Control, Intelligence, Surveillance and Reconnaissance (C2ISR) environment, current sensor platforms have a limited operational capability due to power consumption and recharge times. Many times these sensor packages are found to be unsuitable for many battlefield environments due strictly to their endurance limitations. Much of the research done to date has ...

DESCRIPTION (provided by applicant): Improvements in the safety and efficacy of warfarin therapy will result from intelligent application of knowledge derived from inherited characteristics (CYP2C9 and VKORC1) of individual patients, only when this knowledge is applied through a standardized interventional approach. The fundamental pharmacologic influences of CYP2C9 and VKORC1 have been unequi ...

DESCRIPTION (provided by applicant): In this Phase II STTR project, Vestan Medical Imaging, Inc. will complete the development and clinical evaluation of its proprietary formulation of a fluorescent drug and new medical devices for Sentinel Lymph Node (SLN) biopsy for the surgical treatment of melanoma and breast cancer. Vestan will partner with the University of Utah Huntsman Cancer Institute (HC ...

Bismaleimide (BMI) 5250-4 and epoxy 977-3 material systems are used in F-35 aircraft composite components fabricated via autoclave. Alternative out-of-autoclave processes can reduce manufacturing costs by lowering capital and tooling costs and providing faster cure cycles, if properties can be maintained. Feasibility of the Quickstep out-of-autoclave process for 5250-4 and 977-3 material systems h ...

DESCRIPTION (provided by applicant): Cerebral edema (and its counterpart in the spinal cord) is a major contributor to the damage caused by stroke, traumatic brain injury, traumatic spinal-cord injury, and bacterial meningitis. Stroke alone is the third leading cause of death in the USA and the leading cause of disability. Unfortunately, few treatment options are available for cerebral and spinal- ...

DESCRIPTION (provided by applicant): Critical Limb Ischemia (CLI) is a common problem that often results in major limb amputation. Circulating endothelial progenitor cells likely play a role in the pathogenesis of CLI; the number and function of these cells that are mobilized from the bone marrow are reduced in the elderly and diabetics, groups at high risk for CLI. Allogenic Umbilical Cord Blood ...

DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

Advanced Optical Systems, Inc. (AOS) has developed and demonstrated the Cable Angle Measurement System, a low-cost, accurate system for measuring a helicopter’s load position and motion at the end of an external sling. By using a camera, an LED target, and custom electronics, the AOS system measures the load’s angle with better than 0.1° accuracy across a 150° field of view and with 0.1°/s ...

BUCK-I defines an architecture for an appropriate work-centered support environment, creates an innovative method for human knowledge indexing, defines collaboration technologies and methods, and introduces tools to manage workflow. It is open source, cross platform, and cross-operating system technology. BENEFIT: Successful completion of BUCK-I would provide TDKC with a commercializable produc ...

DESCRIPTION (provided by applicant): The rat is a favored model for many types of human disease for which mice are not suitable. As opposed to the mouse, rats and humans also share more similarity in their cytochrome P450 genes, making the rat a more useful model for toxicology and pharmacology studies. The rat is also a favored model for diabetes, arthritis, behavioral disorders (including drug a ...