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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Additively Manufactured Inflatable Hulls- Improved Survivability- 20% Total Ownership Cost Reduction

    SBC: Response Technologies, LLC            Topic: DLA152001

    Seam failures of flexible inflatable hulls is the primary reason for failures of military RHIBS and CRCs.These failures are a result of the current manufacturing methods being used, and which have been in place for over fifty years.Whats more, the manufacturing methods and fragmented supply chain of these hulls result in very long and unreliable lead times.These shortcomings impact the survivabili ...

    SBIR Phase II 2018 Department of DefenseDefense Logistics Agency
  2. GAA-ITEM: Personalizing the Prediction of Anti-therapeutic Antibody Response in Pompe Disease Patients

    SBC: EPIVAX, INC.            Topic: 999

    Abstract SignificanceInfantile Pompe DiseaseIPDis an autosomal recessive glycogen storage disorder caused by a deficiency of acid alpha glucosidaseGAAleading to accumulation of glycogen in lysosomesprimarily in skeletalcardiac and smooth musclesUntreated IPD infants die within the firstyears of lifeEnzyme replacement therapyERTwith recombinant human GAArhGAAimproves survival and quality of lifebut ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Evidence-Based Pain Intervention for Veterans: Leveraging Mobile & Social Media

    SBC: Pro-Change Behavior Systems Inc            Topic: NCCIH

    Chronic musculoskeletal pain creates a significant public health burdenand Veterans are disproportionately affectedThe frequency and extent of co occurrence of pain and PTSDpain and Traumatic Brain InjuryTBIall three conditionsPost deployment Multi symptom DisorderPMDand other multi symptom syndromes can complicate and reduce the effectiveness of pain treatmentFurthermorethe majority of Veterans d ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Reduced Cost Fabrication of Optical Sapphire Hyper-hemispheres for Submarine Masts

    SBC: ADOLF MELLER COMPANY            Topic: N161036

    The objective of the proposal is to reduce the cost of fabrication of sapphire optical hyper-hemispheres for submarine masts. Due to the nature of sapphire, deriving complex geometries from grown boules using current conventional fabrication techniques is one of the major contributors to cost. Removing excess material requires long diamond tool grinding cycles. New advances in ultrasonic technolog ...

    SBIR Phase II 2018 Department of DefenseNavy
  5. GeoMetrix: Rapid, Reliable, and Global Analytics using Commercial Satellite Imagery

    SBC: Vision Systems, Inc.            Topic: SB162009

    The pace of warfare is increasing rapidly with the emergence of numerous asymmetrical threats exhibiting complex interdependencies and shifting alliances. Never has it been more essential to acquire detailed tactical intelligence in time scales in hours ...

    SBIR Phase II 2017 Department of DefenseDefense Advanced Research Projects Agency
  6. Combining Next-Generation Sequencing and Advanced Algorithms to Elucidate Tumor Heterogeneity

    SBC: Medley Genomics            Topic: 100

    PROJECT SUMMARY Cancer is one of the leading causes of morbidity and mortality worldwideDriven by advancements in quantifying and characterizing the molecular profile of the tumorcancer therapy is becoming more personalizedselectiveand specificA key factor contributing to the lethalitytherapeutic failureand drug resistance of cancer patientshoweveris intra tumor heterogeneityITHcharacterized by a ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Novel Antigen-Specific Immunomodulatory Tregitope-based Therapy to Address Autoimmune Pathogenesis in Graves' Disease

    SBC: EPIVAX, INC.            Topic: 200

    ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

    SBIR Phase I 2017 Department of Health and Human Services
  8. Caring for the Caregiver: A Theory-Driven Mobile Intervention to Promote Caregiver Well-Being

    SBC: Pro-Change Behavior Systems Inc            Topic: NIA

    Overmillion Americans are currently providing unpaid care to a family memberrelativeor friend with Alzheimer s disease or related dementiaWhile caregiving can be a positive experience that brings meaning and an increased sense of purposeit can also take a tollNearlyof Alzheimer s and dementia caregivers rate their emotional distress as high or very highand as many assuffer from depressionCaregiver ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. SnapCap: a device to decontaminate central venous catheters (CVC) with 5 snaps

    SBC: Contech Medical, Inc.            Topic: NICHD

    Project Summary Abstract We propose a new approach to the decontamination of central venous catheters and the prevention of central line associated bloodstream infectionsCLABSIan important healthcare associated infectionCLABSIs cost the US healthcare system approximately $billion annuallyPronovostNEJMAdditionallyCLABSIs can be life threateningespecially in the very young and critically illEven whe ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Next Generation Electronic Warfare Human Machine Interface (HMI) for Submarines

    SBC: SYSTEMS ENGINEERING ASSOCIATES CORPORATION            Topic: N151036

    During Phase I, HMI concepts were developed to facilitate work load sharing, collaboration, and interoperability of tools and displays. Attention was given to simplicity and efficiency to reduce the number of menus and button clicks, eliminate windows, and simplify controls to be more intuitive.In Phase II the conceptual displays will be developed into a fully functioning prototype and integrated ...

    SBIR Phase II 2016 Department of DefenseNavy

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