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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Rapid Prototype Portable Combat and Launch System

    SBC: SYSTEMS ENGINEERING ASSOCIATES CORPORATION            Topic: N95053

    SEA CORP will leverage the innovative technologies developed under the prior SBIR Phase II project and extend the Research & Development (R&D) activities to the development of critical submarine combat system payload integration efforts. In the previous effort, components were successfully developed facilitating integration of Improved Submarine Launched Mobile Mine (ISLMM) capability aboard subma ...

    SBIR Phase II 2019 Department of DefenseNavy
  2. Non-collinear Wave-front Curvature Range Measurement

    SBC: MIKEL, INC.            Topic: N02025

    The goal of this Phase II SBIR is to extract more information from existing submarine acoustic sensors through a highly innovative inter- and intra-sensor correlation algorithmic, in order to provide U.S. submarines with increased acoustic superiority over increasingly quiet adversaries. U.S. adversaries are continuously improving their acoustic quieting technologies through efforts such as marine ...

    SBIR Phase II 2019 Department of DefenseNavy
  3. Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder

    SBC: LOHOCLA RESEARCH CORPORATION            Topic: 150

    DESCRIPTIONprovided by applicantAlcohol Use Disorder affectsof the U Spopulation agesand older and costs society over $billion per year in direct medical costsaccidents and lost productivityCurrent pharmacotherapy is only modestly effective and has to be used in conjunction with psychosocial treatmentPrimary care physicians are ill equipped to provide the currently necessary range of therapy for t ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Clinical optical coherence tomography for retinal metabolic imaging

    SBC: OPTICENT, INC.            Topic: NEI

    PROJECT SUMMARY Diabetic retinopathyDRis a complication of diabetes and a leading cause of blindness in the worldAlthough it is widely accepted that DR is driven by ischemiathe current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR or angiogenesis in proliferative DRAs a resultmost patients have alrea ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. A real-time, cost-effective, accurate UV measurement and sun protection system to prevent and reduce the incidence of sunburn in high-risk consumers.

    SBC: WEARIFI, INC.            Topic: 100

    PROJECT SUMMARY ABSTRACT The US Surgeon General reports that skin cancer is the most common type of cancer in the USThe number of Americans who have had skin cancer at some point over the last three decades is estimated to exceed all other cancers combinedThere are more thannew cases of melanoma each yearresulting in more thandeathsReports indicate that nearlyof skin cancers are caused by UV expos ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Nickel Aluminum Bronze for Additive Manufacturing Alloy Development

    SBC: QUESTEK INNOVATIONS LLC            Topic: N171088

    QuesTek Innovations LLC, a leader in the field of Integrated Computational Materials Engineering (ICME), proposes to design and optimize a new Nickel Aluminum Bronze (NAB) alloy for use as feedstock material in directed energy deposition (DED)-based additive manufacturing (AM) in order to enable the development of AM technologies for quicker, cheaper, and more reliable production and repair of NAB ...

    SBIR Phase II 2018 Department of DefenseNavy
  7. Albumin Nanoparticles Incorporating Piceatannol (PANPs) for ALI/ARDS therapy

    SBC: CELL BIOLOGICS INC            Topic: NHLBI

    Sepsis induced ALI ARDS is a devastating syndrome of acute respiratory failure in critically ill patients that accounts for among the highest admission rates in ICU and mortalityDuring STTR Phasewe at Cell Biologics Incdemonstrated that piceatannola naturally occurring anti inflammatory that selectively inhibits Syk tyrosine kinasewhen entrapped in innm albumin nanoparticlesPANPswas therapeuticall ...

    STTR Phase II 2017 Department of Health and Human Services
  8. Advanced Nucleation Technologies for Membrane Protein Crystallization to Accelerate Structure-Based Drug Design for Substance Use Disorders

    SBC: DENOVX, LLC            Topic: NIDA

    PROJECT SUMMARY The goal of this Phase I proposal is to improve membrane protein crystallization outcomes using bifunctionalhydrophilic hydrophobicself assembled monolayersSAMsas a substrate that interacts with the bicelle envelope and indirectly preconcentrates and preorganizes membrane proteins to facilitate nucleation and crystal growthOf thehuman membrane proteins potentially relevant to drug ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. A Therapeutic Wearable Sensor for Dysphagia

    SBC: Sonica LLC            Topic: NIA

    PROJECT SUMMARYOf themillion individuals worldwide with Alzheimer s disease and related dementiasADRDtotomillion individualssuffer dysphagia or swallowing problemsThe sequelae of dysphagia in this vulnerable population include malnutritiondehydrationand aspiration pneumoniaSince swallowing and breathing share a common anatomical pathwayprecise coordination is criticalIn normal individualsswallowin ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Aircraft Thermal System Evaluation and Analysis Tools

    SBC: CU AEROSPACE L.L.C.            Topic: N19BT025

    This STTR project proposed by CU Aerospace (CUA) and research partner the University of Illinois at Urbana-Champaign (UIUC) will provide innovative thermal management systems-level analysis tools to the Navy, enabling detailed investigations of air platform thermal management issues associated with electronics loads (e.g., avionics/radar upgrades for military aircraft). The Phase I effort focuses ...

    STTR Phase I 2019 Department of DefenseNavy

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