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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Open Source System for Audio Processing

    SBC: CREARE LLC            Topic: NIDCD

    This proposal responds to RFA DCin which the NIDCD is seeking to support the development of acoustic signal processing tools that have the potential to accelerate research studies and to facilitate the translation of novel algorithms for hearing aidsApproximatelyof American adults report some degree of hearing troubleandof Americans agedand over experience bilateral hearing lossHLThehearing aid in ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. Targeting leukocyte metabolism to treat human autoimmune disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has defined an anti MCTmonoclonal antibodymAbthat will be developed for the treatment of human autoimmune diseaseThe membrane monocarboxylate nutrient transporter SLCAMCTis a multi pass transmembrane protein responsible for the facilitated transport of critical metabolitesincluding products of glycolysislactatepyruvate and ketonesOur strong preliminary data support the tenet that mAbs tha ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Development of Military Tactical Eyewear with an Active Anti-fogging System

    SBC: TDA Research, Inc.            Topic: SOCOM18003

    The military combat eye protection (MCEP) program is designed to protect our soldiers' eyes from the external threats of fragmentation, electromagnetic radiation, wind, dust, sand, etc. and greatly improve both safety and operational effectiveness. However, the goggles and spectacles on the Militarys authorized protective eyewear list (APEL) are only effective if the soldier is wearing them. Foggi ...

    SBIR Phase II 2019 Department of DefenseSpecial Operations Command
  4. Large-aperture Electrically Tunable Lenses with 40 Microsecond Hysteresis-free response for Remote Focusing

    SBC: Boulder Nonlinear Systems, Inc.            Topic: 101

    PROJECT SUMMARY This Phase II Lab to Marketplace proposal aims to commercialize a new remote focusing technique that can change the focus of a microscope by as much asm in less thansorders of magnitude faster than other discrete focus change techniquesOur initial market is neuroscience imagingwhere the ability of researchers to step between focal planes at the millisecond timescale of neuronal cir ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. STEM Interactive Digital Tool to Educate and Promote Hearing Health and Science for 4th to 7th Grade

    SBC: CREARE LLC            Topic: 500

    PROJECT SUMMARY ABSTRACT The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instructionproviding virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigationsWith the nationally recognized need to encourage and enhance education in the ScienceTechnologyEngineering ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Adaptable Pediatric Neurocognitive Assessment

    SBC: CREARE LLC            Topic: 103

    PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Development of a Clinical Screening Platform for Type 1 Diabetes

    SBC: Op-T-Mune, Inc            Topic: NIDDK

    AbstractA major shortfall in clinical care for diabetes is a rapid and accurate screen for progression to diseaseCurrent criteria involve HLA haplotypeand the presence of auto antibodiesAAGenome wide associated studiesGWASrevealed only immune associated genes including HLA as T D predictorsThe ability to differentiate from other diseases was very limitedPre typediabetesp T Dis now being identified ...

    STTR Phase II 2018 Department of Health and Human Services
  8. Novel Polymer Matrix for Dental Applications

    SBC: TDA Research, Inc.            Topic: NIDCR

    Project SummaryAbstract Dental caries are the most common childhood disease in the United StatesDental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decayThis method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface whereof the decay developsSealants are safe and effective in p ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Proprietary biologic treatment to heal skin wounds

    SBC: Allander Biotechnologies            Topic: NIDCR

    SUMMARY Chronic skin wounds associated with various diseasese gdiabetesand aberrant healing from acute woundinge ghypertrophic scarringare a major health care burdenThis health burden increases in aging populationsThe cost to treat these conditions exceeds $billion annuallyCurrentlyREGRANEXa cream containing a biologic based on human PDGFPlatelet Derived Growth Factoris the only FDAFood and Drug A ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. Smartphone Help for DWI Offenders and Their Families: A B-SMART App

    SBC: KLEIN BUENDEL, INC            Topic: 450

    Driving while intoxicatedDWIremains a substantial and preventable source of morbidity and mortality in the United StatesA variety of sanctions and interventions have been attempted to reduce DWI in the U Sincluding enhanced DWI enforcement effortsstricter drunk driving lawsresponsible alcohol beverage service trainingand alcohol treatmentThe Ignition Interlock DeviceIIDwhich requires a driver to b ...

    SBIR Phase II 2018 Department of Health and Human Services

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