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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Perinatal brain injury resulting in mental retardation and cerebral palsy is the most severe disability in children and affects 40-148 in preterm and 1–2/1000 in full term infants. This places a huge burden on society, emphasizing the critical need for improved prevention/treatment strategies to decrease perinatal brain injury. Hypothermia (HT) is the only FDA approved therapy to attenuate brain ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Point-of-care lateral flow immunoassay for diagnosis of pertussis

    SBC: DXDISCOVERY INC            Topic: NIAID

    Pertussis (Whooping cough) is a highly contagious, airborne disease that is rapidly re-emerging as a serious public health threat in the United States. Despite high vaccine coverage, annual reported cases in the U.S. have been increasing recently, with an average of 25,000 per year from 2010-2019. This is a level unseen since the early 1960s. Diagnosis of pertussis is challenging because its early ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Affordable, quantitative, point-of-care microchip-electrophoresis for screening and treatment monitoring of sickle cell disease, thalassemias, and anemias

    SBC: HEMEX HEALTH INC            Topic: NHLBI

    PROJECT SUMMARY Anemia is characterized by low blood hemoglobin levels and has a high prevalence, affecting over one-third of the world's population of about 2.5 billion people. More than 7% of the world’s population carry hemoglobin gene mutations that result in hemoglobin variants, one of which is Sickle Cell Disease (SCD). SCD impacts about 100,000 Americans. The trait form of SCD is the Sick ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development and testing of a digitally assisted risk reduction platform for youth at high risk for suicide

    SBC: KSANA HEALTH INC            Topic: 104

    ABSTRACTDespite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Although promising approaches are available for preventative interventions with youth at-risk for suicide, they demonstrate modest benefit, and recent reviews have concluded that new developments are required that facilitate not only greater effectiveness, but also enh ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Acuity- A Clinical Decision Support System for Applied Behavior Analysis

    SBC: Experiad LLC            Topic: 104

    PROJECT SUMMARY / ABSTRACT This proposal will result in a major new clinical decision support software system, Acuity, which will assist Behavior Analysts (BAs) and Behavior Technicians (BTs) in the delivery of Applied Behavior Analysis (ABA), which is the leading treatment for autism. This is a proposal to develop software and perform a functional impact and implementation outcomes study on 34 BA ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: 100

    Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with an incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The α7β1 integrin is a transmembrane linkage system in skeletal and card ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Validation of artificial intelligence (AI) based software as medical device (SaMD) for retinopathy of prematurity (ROP)

    SBC: Siloam Vision, Inc.            Topic: NEI

    The purpose of this application is to perform the necessary clinical studies to seek regulatory approval for an artificial intelligence (AI) software as medical device (SaMD) for retinopathy of prematurity (ROP) diagnosis. ROP is a leading cause of childhood blindness worldwide, with approximately 50,000 babies going blind annually, most of which is preventable with accurate and timely diagnosis. ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Goalspace: A Platform for Parent-Assisted Behavioral Interventions

    SBC: Experiad LLC            Topic: 104

    Experiad will develop a new type of parent engagement platform, called Goalspace, which will facilitate parent- assisted Applied Behavior Analysis (ABA). Goalspace has the potential to have a major impact on autism treatment worldwide by increasing the amount of parent engagement in ABA therapy. Demand for ABA services far exceeds capacity. Parent-assisted ABA is a key evidence-based component of ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Smart Well Assessment and Reservoir Management System (SWARMS)

    SBC: OCEANIT LABORATORIES INC            Topic: 22PH4

    Pipeline and Hazardous Materials Safety Administration (PHMSA) is actively involved in the safe transportation of energy and hazardous material that are vital to daily lives. This also includes underground natural gas storage (UNGS) maintenance and safe operation which are critical to nation's energy infrastructure. Enhancing leak detection and identifying smart ways to prevent potential well blow ...

    SBIR Phase II 2023 Department of Transportation
  10. Thrombopoietin Targeting in Myeloproliferative Neoplasms

    SBC: ARONORA INC            Topic: NHLBI

    Project Summary/Abstract Treatment of patients with myeloproliferative neoplasms (MPNs) is limited to palliative and cytoreductive agents that mitigate proliferative blood counts and their effects. Small molecule selective tyrosine kinase (JAK1/JAK2) inhibitors were also shown to provide modest patient benefit, including reduced symptomatology and improved quality of life. Despite the available th ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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