Award Data

STRIATAL TRANSPLANTATION OF NEUROTRANSMITTER CELLS, IMMUNOISOLATED WITHIN A PERMSELECTIVE POLYMER MEMBRANE CAPSULE, REPRESENTS A NOVEL APPROACH TO THE TREATMENT OF PARKINSON'S DISEASE. THE TECHNIQUE HAS HAD PROMISING RESULTS IN SEVERAL RODENT MODELS, AND PRIMATE STUDIES ARE UNDERWAY. THE OVERALL OBJECTIVE OF THIS RESEARCH IS TO COMPLETE THE DEVELOPMENTS NECESSARY FOR WIDESPREAD MEDICAL ACCEPTANCE ...

THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS THE DEVELOPMENT AND INTRODUCTION TO MEDICAL PRACTICE OF AN EFFECTIVE BIOCOMPATIBLE IMPLANTABLE HYBRID ARTIFICIAL ENDOCRINE PANCREAS THAT IS CAPABLE OF SIGNIFICANT IMPROVEMENT IN THE THERAPY OF INSULIN-DEPENDENT DIABETES. THE SPECIFIC AIM OF THIS PROJECT IS TO EXTEND AND MODIFY A PROCESS FOR CELLULAR ENCAPSULATION TO THE ISLETS OF LANGERHANS, USING A CO-E ...

OCCUPANT PROTECTION IN VEHICULAR SIDE IMPACT CRASHES IS AN IMPORTANT THEME OF THE '90S FOR THE DEPARTMENT OF TRANSPORTATION, FOR AUTOMAKERS, AND FOR INDEPENDENT RESEARCHERS. DEVELOPMENT OF OCCUPANT PROTECTION METHODS REQUIRES ACCURATE MEASUREMENT OF CONTACT VELOCITY IN SIDE IMPACT TESTS. MICROWAVE INTERFEROMETRY (MI) IS PROPOSED AS A MEANS TO MEASURE DOOR/OCCUPANT VELOCITIES IN SIDE IMPACT TESTS. ...

THE USE OF POROUS COATINGS TO PROVIDE THE ATTACHEMENT MECHANISM FOR REPLACEMENT OF DISEASED JOINTS HAS INCREASED DRAMATICALLY IN THE PAST FEW YEARS, AND IT IS EXPECTED TO CONTINUE TO DO SO IN THE FUTURE. THERE ARE 300,000 HIP AND KNEE REPLACEMENTS PERFORMED ANNUALLY IN THE UNITED STATES, AND IT IS ESTIMATED THAT 50 PERCENT OF THESE IMPLANTS RELY ON BONE INGROWTH AS THE MECHANISM OF ATTACHMENT BETW ...

DURING THIS PERIOD 1983 TO 1987, THE NUMBER OF DENTAL IMPLANTS INSERTED IN THE UNITED STATES INCREASED 4-FOLD AND THE NUMBER OF PRACTITIONERS PERFORMING IMPLANTS INCREASED 10-FOLD. FURTHERMORE, IT IS ESTIMATED THAT 300,000 OR MORE DENTAL IMPLANTS WILL BE USED IN THE UNITED STATES BY 1992. OSSEOINTEGRATION, PARTICULARLY IN TWO-STAGE ROOT-FORM IMPLANTS, HAS BEEN SHOWN TO RESULT IN EXCELLENT PERFORMA ...

THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO PROVIDE AN UP-TO-DATE COMPREHENSIVE ACCOUNT AND EVALUATION OF DIFFERENT BIOLOGICAL PARAMETERS AND THEIR COMBINATIONS USED AS INDICATORS OF ALCOHOL ABUSE AND ALCOHOLISM. IN PHASE I, THE PROJECT WILL IDENTIFY THE PERTINENT SCIENTIFIC LITERATURE AND THEN PROVIDE A REVIEW AND CRITICALEVALUATION OF THE MAJOR FINDINGS IN DIFFERENT STUDIES, ESPECIALLY IN REG ...

KVH INDUSTRIES PROPOSES TO THOROUGHLY INVESTIGATE BOTH CONVENTIONAL AND INNOVATIVE USES FOR THE SELF POWERED VEHICLE DETECTOR (SPVD) AND TO MODIFY THE EXISTING DESIGN, IF REQUIRED, TO MEET THE SPECIFICATIONS OF THE NEW APPLICATIONS. THE OVERALL GOAL OF THE PROPOSED SBIR PHASE IEFFORT CAN BE SUBDIVIDED INTO THREE FUNDAMENTAL OBJECTIVES: RESEARCH INTO THE VARIOUS APPLICATIONS OF SPVD TECHNOLOGY AND ...

THIS PROGRAM WILL COMPILE A RESOURCE GUIDE IDENTIFYING LOW-COST DEVICES OR PRODUCTS THAT COULD PROVIDE GREATER INDEPENDENCE FOR DEVELOPMENTALLY DISABLED PERSONS. THE RESOURCE GUIDE WILL DESCRIBE THE ADAPTIVE DEVICES BY COST, TYPE, AND DISABILITY. THE PROGRAM WILL ALSO DESIGN AND DEVELOP A LOW-COST DEVICE TO ASSIST HANDICAPPED INDIVIDUALS WITH LIMITED OR NONEXISTENT FINGER DEXTERITY TO PICK UP AND ...

AN INCREASING NUMBER OR WHEELCHAIR-BOUND STUDENTS ARE ATTENDING PUBLIC SCHOOLS, A PROCESS KNOWN AS "MANINSTREAMING". CONSEQUENTLY, PROTECTING THESE STUDENTS IN THE EVENT OF A SCHOOL BUS COLLISION IS A SIGNIFICANT SAFETY ISSUE. EXISTING RESTRAINT SYSTEMS TEND TO FOCUS ON RESTRAINING THE WHEELCHAIR RATHER THAN THE OCCUPANT. DISCUSSED IN THIS PROPOSAL IS A SYSTEM TO PROTECT A WHEELCHAIR STUDENT INVOL ...

THIS PROJECT IS CONCERNED WITH A PATIENT DATABASE SYSTEM FORCARE PLANS AND MEDICAL RECORDS IN NURSING HOMES, HOME CARE INSTITUTIONS, AND SUBACUTE CARE FACILITIES. THE SYSTEM ALSOINCLUDES HANDLING OF DEMOGRAPHIC INFORMATION, CENSUS REPORTS, PATIENT ASSESSMENTS, AND CARE PLANS. THE CARE PLANS ARE BASED ON AN HIERARCHICAL STRUCTURE OF DIAGNOSIS, PROBLEMS, GOALS, AND APPROACHES. THE SYSTEM ALLOWS THE ...