Award Data

The DoD Chemical, Biological, Radiological, and Nuclear Defense Program Performance Plan discusses the status of sensing technologies and long-term goals, and shows point biological detection systems are expected to provide 20% of the objective capabilities in FY15. This indicates that there is the need for a man-portable, disposable, rapidly responding biological agent point detector that is capa ...

Photon-X is proposing to develop an innovative dynamic 3D roof imaging system to monitor vehicle roof deformation during vehicle rollover testing. The 3D imaging system will capture real-time dynamic motion of the roof and vehicle occupants for playback analysis or modeling to enhance overall safety in rollover crashes. The system will provide photographic resolution 3D imagery with the ability ...

The objective of this work is to develop a low cost 6 DOF body tracking system to monitor the orientations of an occupants and pedestrians as well as vehicle kinematics in vehicular impact tests. This tracker system can be standalone or part of a subsystem that can communicate with other trackers and external computer via serial, USB and/or Bluetooth interface. The proposed tracker coined Body O ...

Positioning and navigation have become a mainstay of everyday life in the U.S.; applications of interest include navigation of vehicles of all kinds, infrastructure mapping, and safety of life systems. Many of these recent applications have become possible through the GPS. With the recognized vulnerabilities of GPS, it is evident that equivalent backup systems must be developed. One possible so ...

DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) has recently developed and patented a technology platform for engineering fluorogenic functionality into living Bacillus spores. Fluorogenic spores (F-spores) produced at BCR appear to be phy siologically identical to normal spores except for performing as self reporters of initial germination events. Considering the unique features ...

DESCRIPTION (provided by applicant): Breast cancer is the leading cause of cancer deaths in the United States. In this year alone, approximately 40,480 women in the US are estimated to die from breast cancer. In most cases, death results from metastasis of breast cancer cells. Cancer patients with metastasis cannot currently be cured. Therefore, the invention of therapy to treat breast cancer met ...

DESCRIPTION (provided by applicant): Optical imaging as a noninvasive diagnosis technique is a highly promising tool for real-time, in-vivo detection of tumor margins during breast-conserving surgery. This can decrease false-negative diagnoses and local re currences of the cancer that occur after conventional diagnoses and lumpectomy. Its clinical application has been held back by lack of suitable ...

DESCRIPTION (provided by applicant): One of the main challenges in the discovery of intracellular biomarkers and identification of therapeutic targets is the lack of a mechanistic understanding of the complex underlying pathways. The tremendous increase in both the quantity and diversity of cellular data represents a significant challenge to researchers seeking to construct biologically relevant ...

DESCRIPTION (provided by applicant): Sodium Transport Inhibitors for Hypertension and Cystic Fibrosis Scientific Summary Description Hypertension is a confounding multifactorial disorder that affects millions of patients worldwide. Cystic fibrosis (CF) is an inherited disease of the pulmonary and gastrointestinal systems that presents in pediatric and young adult populations. What do hypertension ...

DESCRIPTION (provided by applicant): The overall goal of this project is to develop and commercialize a software package to be interfaced with commercial MRI scanners providing physicians with an immediately available diagnostic tool for noninvasive detec tion, lateralization, and quantification of epileptogenic tissue. This software would convert a set of 2D MRI images of the brain to a 3D perce ...