Award Data

ABSTRACT: The Tai-Yang Research Company (TYRC) of Tallahassee, FL in collaboration with Dr. Justin Schwartz of the North Carolina State University (NCSU) in Raleigh, NC propose in this Phase 2 effort to develop the critical technologies necessary for the implementation and operation of an airborne high temperature superconductor (HTS) superconducting magnetic energy storage (SMES) device with par ...

YTP will develop technology that provides a high performance, modular Li-ion battery with: redundant safety features, safer thin, metal case cell designs; fin/micro-channel thermal control system; and an evaporating fluid system that rapidly quenches failing cells to prevent thermal runaway and fratricide. The end goal of the proposal is making a lighter, longer lasting, less expensive, safer JSF ...

ABSTRACT: With the tremendously successful Phase I effort, Third Dimension Technologies (TDT), in collaboration with Lockheed Martin, Rickard Consulting Group and APTUS, plans in Phase II to create, test and evaluate a gaming-based training and rehearsal environment known as the W3DGE (Warfighter 3D Gaming Environment). The Air Force has a need for a lower-cost, more deployable tactical training ...

ABSTRACT: VSI proposes the development of the SIGMA (Speedy Imagery Geo-registration and Motion Analysis) system, which will address three key requirements by the end of Phase II: (i) adapt to different type of sensors, sensor-configurations and sensor operating conditions, (ii) handle large amount of data in real-time or close to real-time using limited resources, and (iii) operate under conditi ...

DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

Marous, James R. An Eye Bank Endothelial Cell Counter Abstract Procurement of donor corneal tissue for transplant use is an important social service undertaken by largely underfunded eye banks. Tissue is not only harvested, but must be screened for a myriad of issues that may make the tissue unsuitable for transplant or pose a health risk to the tissue recipient. Donor tissue may be rejected for ...

Project Summary/Abstract Medical students long ago gave up robbing graves for corpses, but students still need access to anatomy resources. While availability of traditional resources (e.g. cadavers, animals, etc.) is dwindling, emerging virtual alternatives are revolutionizing the practice of medicine. Interest in virtual aids derives from decades of success in aviation and the military. These in ...

DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

? DESCRIPTION (provided by applicant): The goal of this Phase I STTR project is to establish the feasibility of developing a small-molecule therapeutic agent designed to prevent rhabdomyolysis-induced renal failure. Rhabdomyolysis accounts for 7% to 10% of cases of renal failure in the US. Rhabdomyolysis results from muscle injury that leads to the release of myoglobin, which is then deposited ...

DESCRIPTION (provided by applicant): There is an urgent, unmet need for novel therapeutic approaches that are efficacious against lung cancer. Ranking first among cancer deaths in the U.S., this disease has 5-year relative survival rates of lt20%. Most lung cancers are non-small cell (NSCLC, 85% of cases). Curative surgery is not an option for the 80% of NSCLC patients who present with advanced s ...