Award Data

Carbon seals generlly used for bearing compartments will incrasingly become unsuitable for future gas turbine engines with higher buffer air temperatures, higher pressur and rotor surface speeds.Phase I effort will focus on a synergistic approach including advanced materials and design.Three materials including a (Ti,Mo)(C,N) cermet, B-C composite and a current high temperature grade carbon MAT-12 ...

Appareo Systems, LLC, proposes to develop a functional prototype head-mounted position and orientation system (HPOS). The HPOS will be capable of operating in electromagnetic fields of up to 200 volts/meter and will provide at least one degree of accuracy and at least one degree of resolution at a 60 Hz update rate while providing 3 degree of freedom (DOF) information on head orientation, includi ...

DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) has recently developed and patented a technology platform for engineering fluorogenic functionality into living Bacillus spores. Fluorogenic spores (F-spores) produced at BCR appear to be physiologically identical to normal spores except for performing as self-reporters of initial germination events. ...

DESCRIPTION (provided by applicant): This new Phase I SBIR proposal addresses the continuing worldwide need for a tuberculosis (TB) vaccine. We detail a novel multivalent strategy that aims to elicit immunity to prevent reactivation of latent TB. This epitope-driven, DNA-prime, protein-boost TB vaccine has been in development since 1997, when our immunoinformatics tools were first applied to ident ...

DESCRIPTION (provided by applicant): Hemophilia A patients are prone to develop inhibitory immune responses to the very therapy they require: Factor VIII protein replacement. Up to 30% of all hemophiliacs and greater than 50% of severe hemophiliacs produce antibodies (inhibitors) in response to treatment. Immunogenicity to Factor VIII (FVIII) is its most significant complication: immunogenicity no ...

This SBIR Phase I proposal requests $99739 for Flight Safety Technologies, Inc. to investigate the feasibility and all-weather capability of a novel radar concept as an active, non-cooperative SAA sensor for UAVs. The concept radar, which we call Unicorn, is a narrow-band pulsed radar operating around a center frequency of 5.145 GHz in the aviation C-band, which has been approved for this develop ...

DESCRIPTION (provided by applicant): SBIR Abstract for DATACORP's Data Documentation Database (D3) Data documentation is an intricate and time-consuming task. Practical experience has shown that research studies frequently save time and financial costs by delegating the task to less experienced staff or by incompletely documenting the data. Yet poor documentation threatens the data's integrity, le ...

DESCRIPTION (provided by applicant): Myomics' drug screening technology to be developed in this Phase 1 SBIR project for Duchene muscular dystrophy (DMD) is based upon an in vitro skeletal muscle tissue force measurement technique for high content screening (HCS) of compounds to attenuate muscle weakness. Currently, there are few drugs besides Prednisone which are used clinically to slow muscle we ...

DESCRIPTION (provided by applicant): The rationales for the development of technology that will enable extremely cheap, high speed sequencing are well established. Chief among these is the enablement of personalized medicine. There are currently in development several technologies that promise to markedly decrease the cost of sequencing a human genome. It is unclear, however, that any of these wil ...

DESCRIPTION (provided by applicant): Low birthweight and preterm birth are unfavorable birth outcomes that translate into serious and costly health issues, including infant morbidity and infant mortality. Research demonstrates that the health behaviors of pregnant women are associated with not only birth outcomes, but also the future health of the child. The goal of this research is to develop an ...