Award Data

ABSTRACT: In ISR applications, multiple sensors can be employed to achieve more accurate parameters of interest on targets, improving discrimination and detection. But, the proliferation of sensor systems has created a large volume of multi-sensor data across a number of physical spectra. These resulting measurements can be so disparate that traditional aggregation methods perform poorly given h ...

ABSTRACT: UltraHiNet, LLC (UHN) proposes to develop a prototype next generation tracking architecture which exploits wide area motion imagery (WAMI) systems and leverages projected heterogeneous high performance computing (HPC) architectures for on-board and ground-based processing of vehicle and dismount targets for urban surveillance. Our research team will focus on the following goals: 1. Dev ...

ABSTRACT: Information systems continue to progress in terms of collecting, characterizing and assessing information. While this evolution has provided unprecedented intelligence capability to the U.S. and our allies, it has also raised unique challenges in the area of information security and disclosure risks. In particular, the intelligence community (IC) currently lacks the ability to understan ...

ABSTRACT: The ability to obtain time-resolved, direct wall shear stress measurement is an important asset to aerodynamic research, flow control and to enhance the fundamental understanding of the turbulent boundary layer. Due to a lack of reliable and affordable skin friction sensors, existing indirect methods are used to measure wall shear stress but their usefulness is limited since prior kno ...

DESCRIPTION (provided by applicant): Due to its asymptomatic nature and lack of methods for early detection, gt 80% of pancreatic cancer (PC) patients present with an unresectable primary tumor with distant metastasis at the time of diagnosis. While the overall 5 year survival rate of pancreatic cancer is dismal, significantly better outcomes have been reported for smaller tumors detected at an e ...

MTI-101 is a cyclic beta-hairpin peptide that binds CD44 with high affinity and kills multiple myeloma cell lines in vitro and blocks the growth of myeloma tumors in 2 different murine models. This interaction of MTI-101 with the surface of MM cells causesprogrammed cell necrosis, whereas all approved MM drugs cause apoptosis and so the novel mechanism of MTI-101 or MTI-like compounds makes it esp ...

PROJECT SUMMARY Spinal cord injury (SCI) is a complex and devastating clinical condition mediated by proinflammatory cytokines that produce neuronal loss, axonal destruction, and demyelination during the secondary injury cascade. There are currently no proven therapies targeting posttraumatic inflammation that have been shown to have clinical value. We have previously shown that central nervous sy ...

ABSTRACT: IRradiance Glass, Inc. proposes a Phase I STTR program in conjunction with the University of Central Florida to demonstrate the feasibility of the design, development, and production of high numerical aperture (NA) cylindrical lenses for use in the mid- to long-wave infrared optical region by extruding chalcogenide glasses into a micro-lens shape (~2mm wide x 2 mm high x 3 mm long) with ...

ABSTRACT: Information systems continue to progress in terms of collecting, characterizing and assessing information. While this evolution has provided unprecedented intelligence capability to the U.S. and our allies, it has also raised unique challenges in the area of information security and disclosure risks. In particular, the intelligence community (IC) currently lacks the ability to understand ...

DESCRIPTION provided by applicant Technology to deliver molecules andquot on demandandquot that bind to targets or catalyze reactions of a technologistandapos s choosing would have enormous commercial value in research manufacturing and medicine Thus this has been a andquot holy grailandquot of molecular science for a half century Even today chemical theory is inadequate to support de ...