Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Cell-Safe Life Sciences LLC            Topic: NIDDK

    DESCRIPTIONprovided by applicantThe Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetesby transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluidblood ultrafiltrateso that the cells ae protected from immune rejection ...

    STTR Phase II 2017 Department of Health and Human Services
  2. A mobile app to reduce treatment-related financial burden for cancer patients

    SBC: Vivor, Llc            Topic: NCI

    There is a fundamental knowledge gap in how to immediately reduce cancer patientstreatment related financial burdenCancer patients pay more out of pocket for their care than those with other chronic illnessesHalf of all elderly cancer patients have high treatment related out of pocket financial burdenThis financial burden has well defined harmful effects even among insured cancer patients includin ...

    STTR Phase II 2017 Department of Health and Human Services
  3. Study of the New HDAC i SW as a Treatment for Alzheimer's Disease and Other Tauopathies

    SBC: Starwise Therapeutics LLC            Topic: NIA

    ABSTRACT Alzheimerandapos s and other tauopathies are medical problems growing to historical proportions that threaten the long term viability of medical care systems world wide Alzheimerandapos s costs today are of the US GDP and growing as the population ages Effective disease modifying treatments have yet to be developed A number of drugs in clinical testing target amyloid but very fe ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. In Home Reading Eye Movement Training System

    SBC: Kilbride, Paul            Topic: N

    Given the rapidly aging population and the incidence of age related eye diseases the number of individuals with low vision is expected to increase dramatically in the next decades Patients with central vision loss can no longer use their foveas and eccentric retina must be used to perform visual tasks Since the peripheral retina has reduced sensory capabilities and altered oculomotor behavior ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Using a novel model of antidepressant efficacy to discover new compounds and personalized treatments.

    SBC: PAX NEUROSCIENCE, INC.            Topic: 102

    The World Health Organization estimates that bymajor depressive disorderMDDwill be the most common cause of disabilityworldwideAlthough approximatelyinAmericans will suffer from MDD during their lifetimemany patients with MDD go undiagnosed in primary care settingsandare incorrectly diagnosed with MDDGiven the substantial medicaleconomic and social costs involved with MDDthere is tremendous need f ...

    STTR Phase I 2017 Department of Health and Human Services
  6. Wireless implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary Abstract Diseases of the central and peripheral nervous systems affect the quality of life of millions of people worldwide Progress in understanding the function of neural networks and in developing associated insights into the underlying causes of these diseases can be accelerated by advances in techniques and methodologies for neuroscience research Collaborative efforts between ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. The Patient Centered Postpartum Contraception ToolKit PC

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: NICHD

    Project Abstract Short interpregnancy intervals IPIs pose risks for mothers and newborns alike including preterm birth low birth weight small for gestational age and placental abruption IPIs of less than months increase risk of neonatal death Short IPIs are a source of major health disparities and disproportionately affect African American adolescents Postpartum contraception signific ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Prognosis an interactive digital public health and epidemiology adventure

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: OD

    Project Abstract The proposed Phase I STTR project will develop the serious game Prognosis and its supporting website to improve systems thinking and problem solving through learning about public health and epidemiology Prognosis is a simulation game that focuses on the population health of the fictional city Hexacago Through game play players will learn how multiple ambient citywide systems ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Albumin Nanoparticles Incorporating Piceatannol (PANPs) for ALI/ARDS therapy

    SBC: Nano Biotherapeutics, Inc.            Topic: NHLBI

    Sepsis induced ALI ARDS is a devastating syndrome of acute respiratory failure in critically ill patients that accounts for among the highest admission rates in ICU and mortalityDuring STTR Phasewe at Cell Biologics Incdemonstrated that piceatannola naturally occurring anti inflammatory that selectively inhibits Syk tyrosine kinasewhen entrapped in innm albumin nanoparticlesPANPswas therapeuticall ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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