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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Chalcogenide Glass Mid-IR Optic Development

    SBC: Rochester Precision Optics, LLC            Topic: AF15AT06

    The objective of this proposal is to continue the development and prove the manufacturability of fast axis collimating lenses for quantum cascade lasers (QCL) which emit in the midwave-infrared (MWIR) range. These lenses must withstand the stress of both continuous wave (CW) and pulsed laser emission. These high laser powers may cause ablation of lens material reducing effectiveness of the optic a ...

    STTR Phase II 2017 Department of DefenseAir Force
  2. Science Take-Out Kits for Environmental Health Education

    SBC: Science Take-Out, LLC            Topic: NIEHS

    ABSTRACT Nearlypercent of death and diseaseworldwideis linked to environmental factorsWHOthereforeit is critical that the general public has a basic understanding of how the environment affects their health and how they might protect themselves against environmental exposuresUnfortunatelyenvironmental health is typically covered minimallyif at allin secondary school classroomsMartinaand there are ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Discovery of Novel Drugs for Autism

    SBC: ASDDR, LLC            Topic: 101

    Summary The goal of this study is to discover novelmechanism based pharmacological intervention for autisma devastating neurodevelopmental disorder with no treatment currentlyGenetic sequencing has revealed extensive overlap in risk genes for autism and for cancermany of which are chromatin remodeling factors important for transcriptional regulationsuggesting the possibility of repurposing the ant ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement

    SBC: POLYNOVA CARDIOVASCULAR INC            Topic: NHLBI

    Project SummaryA Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacementTAVRhas emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosisASRecent longitudinal follow up studies of TAVR patients however indicate that this procedure and associated technology may result in serious a ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. WARP: Weaving Application-specific Runtime Policies

    SBC: GRAMMATECH INC            Topic: AF16AT19

    Embedded systems are critical to national security and personal safety. However, the level of security provided by most embedded systems is low. In this project, we are building WARP, a tool for Weaving Application-specific Runtime Policies into embedded systems binaries. WARP enables end users to formulate and enforce custom run-time policies that protect the software from external attacks and in ...

    STTR Phase II 2017 Department of DefenseAir Force
  6. Preclinical Development of a Novel Small Molecule Drug for Sepsis

    SBC: THERASOURCE, LLC            Topic: 300

    PROJECT DESCRIPTIONThis STTR Phase I proposal is intended to demonstrate the feasibility of developing tanshinone small molecule analogTSAas an effective and safe small molecule therapy for patients with sepsis and septic shockIn the USmore than one million people develop sepsis every yearYetno effective anti sepsis treatment exists other than antibiotics and supportive careWe have discovered that ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Thunderlane Phase II

    SBC: ASSURED INFORMATION SECURITY, INC.            Topic: AF16AT11

    The Thunderlane Phase II effort defines a new hypervisor model that dissolves the boundary between hypervisor and operating system, and leverages state-of-the-art software diversity techniques for increased resistance to exploitation. The most widely used operating systems (e.g., Microsoft Windows and Linux) use monolithic kernel architectures that execute most system software with full root-level ...

    STTR Phase II 2017 Department of DefenseAir Force
  8. A novel product for tendinopathy treatment

    SBC: NEW YORK R & D CENTER FOR TRANSLATIONAL MEDICINE & THERAPEUTICS INC            Topic: NIA

    Project Summary This study aims to prove the concept and feasibility that TendonCure extracellular vesicles that contain signaling molecules i e exosomes secreted by mesenchymal stem cells i e tendon stem progenitor cells TSPCs or adipose derived stem cells ADSCs from individual patients donors cultured on a novel scaffold exert therapeutic efficacy on tendinopathy when injected into ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Structure based optimization of a novel pharmacological chaperone therapy for MPSIIIC

    SBC: Phoenix Nest Inc.            Topic: NICHD

    PROJECT SUMMARY Lysosomal storage diseases LSD are rare inherited metabolic disorders caused by defects in the cellular catabolic system Mucopolysaccharidosis Type IIIC MPS IIIC or Sanfilippo disease type C is one such LSD that is caused by deficiency of the enzyme heparan sulfate acetyl CoA glucosaminide N acetyltransferase HGSNAT essential for degradation of heparan sulfate a repeati ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Improvements to Biopharmaceutical Manufacturing

    SBC: HocusLocus Inc.            Topic: 400

    PROJECT SUMMARY Over $billion dollarsworth of biological productsincluding antibodiesvaccines and proteinsare produced each yearThis continues to grow worldwide at aboutyearmaking biopharmaceuticals a fairly recession proofgrowing and pro table industryThis shift towards biopharmaceuticals re ects a fundamental shift within the pharmaceutical industryBiomanufacturers are under constant pressure to ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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