Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Remote Brief Intervention and Referral to Treatment Service for Alcohol (R-BIRT)

    SBC: POLARIS HEALTH DIRECTIONS, INC            Topic: NIAAA

    DESCRIPTIONprovided by applicantSignificanceThe USPHSTFSAMHSACDCand NIAAA have affirmed the importance of screening in medical settings for alcohol consumption that exceeds the NIAAA low risk limitsbrief educational and motivational counseling for those who screen positive or have other evidence of an Alcohol Use Disorderandwhen appropriatereferral to treatmentSBIRTHowevertranslation to clinical p ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Biodegradable gold nanoparticles as contrast agents for CT

    SBC: PolyAurum LLC            Topic: NIBIB

    PROJECT SUMMARY Computed tomography is used in about million imaging studies per year in the USA Iodinated contrast agents are used in roughly half of these studies Computed tomography is particularly important for the diagnosis of coronary artery disease where it depends on the use of iodinated contrast agents to visualize the arteries However these agents have a number of shortcomings s ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Polaris Oncology Survivor Transition POST System

    SBC: POLARIS HEALTH DIRECTIONS, INC            Topic: 100

    DESCRIPTION provided by applicant By January oncology care providers will be expected to craft Survivorship Care Plans SCPs for all individuals ending active treatment for cancer however there is a lack of systematic study of the impact survivorship planning has on patients providers or healthcare systems The Polaris Oncology Survivorship Transition POST program is a web based sy ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Therapeutic Mabs for Chronic Kidney Disease

    SBC: OPSIDIO LLC            Topic: 400

    Abstract Opsidio LLC is commercializing a monoclonal antibody MAb that will prevent and treat chronic kidney disease CKD that can lead to end stage renal disease ESRD and dialysis or kidney transplantation At the present time there is no known therapy for CKD that can alter the progression to end stage kidney failure The CDC estimates that there are million adult patients with CKD in t ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Preparation of site specific antibody drug conjugates by proximity based sortase ligation

    SBC: AlphaThera            Topic: 103

    There has been growing interest in the use of antibody drug conjugates ADCs for the treatment of cancer as mounting data suggests an increase in anti tumor effectiveness and reduced toxicity compared with the administration of unlabeled antibodies in combination with chemotherapy The two ADCs that are currently approved by the FDA brentuximab vedotin Adcetris and ado trastuzumab emtansin ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. An Accessible Digital Intervention to Promote HIV Testing/Counseling and Prevention Among Adolescents

    SBC: Schell Games LLC            Topic: NICHD

    Abstract HIV disproportionately impacts minority adolescentsand most of them have neither undergone HIV testing and counselingHTCnor know their statusAdolescence is a "window of opportunity" to intervene with HIV behavior change interventionsChallenges to implementing and disseminating some effective HIV prevention programs in adolescents may limit their impactTo address these challengesinnovative ...

    STTR Phase II 2017 Department of Health and Human Services
  7. Effects of LGM on a Primate Model of Asthma

    SBC: Lignamed, LLC            Topic: NIAID

    PROJECT SUMMARY We previously demonstrated in mice that the major pathogenic features eosinophilic airway inflammation and airway hyperresponsiveness AHR were markedly enhanced in mice exposed to repeated social stress and these changes were associated with impaired glucocorticoid receptor GR expression and function In studies on non human primates rhesus macaques at the California Natio ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. eHealth Mobile Technology Connecting Young Adults to Routine Engagement eMCARE a theoretically and empirically driven mobile intervention to engage young adults in healthcare

    SBC: NuRelm Inc.            Topic: NICHD

    eMCARE EHealth Mobile Technology Connecting Young Adults to Routine Engagement Young adults YAs ages have a worse health profile than adolescents or adults in their late twenties and thirties Most YAs in the US experience no preparation for the transition from pediatric to adult care often seeking care only through emergency department ED visits The results can be seen across issues ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Phase Transitions, Nucleation and Mixing Modeling through Trans-Critical Conditions

    SBC: COMBUSTION RESEARCH AND FLOW TECHNOLOGY INC            Topic: AF14AT23

    The goal of this Phase II effort is to achieve significant improvements in our understanding and modeling of trans-critical combustors operating at high pressure in regimes of interest to the Air Force.There are three main objectives we pursue:1) The use ofmolecular dynamic models as a predictive tool for thermodynamic and transport properties of mixtures, 2) Improved liquid/gas interface models a ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Inhibitors of Hydrogen Sulfide Metabolism as a Novel Treatment for Heart Failure

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: NHLBI

    The goal of this Phase I STTR grant application is to capitalize on our recent discovery of novel sulfide quinone oxidoreductase SQOR inhibitors by the design and preparation of new analogs for the treatment of heart failure that enable us to understand SAR so as to improve potency and optimize ADME PK properties Heart failure is a highly lethal disease affecting more than million adults in t ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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